4-(Trifluoromethoxy)benzenesulfonyl chloride Chemical Properties

Boiling point:

120-122 °C (15 mmHg)

Density 

1.536 g/mL at 25 °C (lit.)

vapor pressure 

0.23 psi ( 20 °C)

refractive index 

n20/D 1.479(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

form 

clear liquid

color 

Colorless to Light orange to Yellow

Specific Gravity

1.536

Sensitive 

Moisture Sensitive

BRN 

7641524

InChI

1S/C7H4ClF3O3S/c8-15(12,13)6-3-1-5(2-4-6)14-7(9,10)11/h1-4H

InChIKey

UHCDBMIOLNKDHG-UHFFFAOYSA-N

SMILES

FC(F)(F)Oc1ccc(cc1)S(Cl)(=O)=O

CAS DataBase Reference

94108-56-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzenesulfonyl chloride, 4-(trifluoromethoxy)-(94108-56-2)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45-39-37-36

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

Hazard Note 

Corrosive/Moisture Sensitive

HazardClass 

8

PackingGroup 

II

HS Code 

29093090

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Eye Dam. 1
Skin Corr. 1B

MSDS

• Language:English Provider:4-(Trifluoromethoxy)benzene-1-sulfonyl chloride
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-(Trifluoromethoxy)benzenesulfonyl chloride Usage And Synthesis

Chemical Properties

Clear colorless to pale yellow liquid

Synthesis

In a 2000mL four-necked flask, 400g (3.84mol) hydrochloric acid, 10g (0.0587mol) copper chloride and 80.0g (0.769mol) sodium bisulfite were added sequentially as a substrate, and 500g of the diazotization reaction solution was added dropwise to the substrate under stirring at -20~5??, and the dropwise addition was completed in 5h, and the temperature was kept warm for 1h, and the oil layer was divided into layers at rest. Oil layer, add 400g of water, stirring 0.5h, static stratification 0.5h, the separation of oil layer, to obtain 142g (content 88%) 4-(trifluoromethoxy)benzenesulfonyl chloride, yield 84.9%.

4-(Trifluoromethoxy)benzenesulfonyl chloride(94108-56-2)Related Product Information

• 4-(Trifluoromethoxy)benzaldehyde
• 4-(Trifluoromethyl)benzene-1-sulfonyl chloride
• 4-(Trifluoromethoxy)chlorobenzene
• (Trifluoromethoxy)benzene
• Benzenesulfonyl chloride
• alpha,alpha,alpha-Trifluoro-o-toluoyl chloride
• 4-(Trifluoromethoxy)aniline
• N-Acetylsulfanilyl chloride
• 4-Chlorobenzenesulfonyl chloride
• 4-Methoxybenzenesulfonyl chloride
• p-Trifluoromethoxy phenol
• Sodium chloride
• Allylbenzene
• Calcium chloride
• Ammonium chloride
• 4'-(Trifluoromethoxy)acetophenone
• Ethylbenzene
• Polyvinyl chloride