3-Bromo-2-fluorobenzoic acid Chemical Properties

Melting point:

168 °C

Boiling point:

298.2±25.0 °C(Predicted)

Density 

1.789±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

2.88±0.10(Predicted)

color 

White to Light yellow

InChIKey

UVKURTLVTLRSSM-UHFFFAOYSA-N

CAS DataBase Reference

161957-56-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

HazardClass 

IRRITANT

HS Code 

2916399090

MSDS

• Language:English Provider:ALFA

3-Bromo-2-fluorobenzoic acid Usage And Synthesis

Chemical Properties

Off-white powder

Uses

3-Bromo-2-fluorobenzoic acid is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 3-Bromo-2-fluorobenzoic acid is also used as a reagent to prepare Alkynlphenoxyacetic acid receptor agonists, compounds that can be potentially used for the treatment of allergic inflammatory diseases (such as allergic rhinitis).

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