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N-BOC-4,4-difluoro-L-proline

Basic information Safety Supplier Related

N-BOC-4,4-difluoro-L-proline Basic information

Product Name:
N-BOC-4,4-difluoro-L-proline
Synonyms:
  • BOC-4,4-DIFLUORO-L-PROLINE
  • BOC-L-PRO(4,4-DIFLUORO)
  • (2S)-Boc-4,4-difluoro-pyrrolidine-2-carboxylic acid
  • (S)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid
  • N-BOC-4,4-DIFLUORO-L-PROLINE
  • N-T-BOC-4,4-DIFLUORO-L-PROLINE
  • N-Boc-4,4-difluoro-L-proline, 97+%
  • (S)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid
CAS:
203866-15-3
MF:
C10H15F2NO4
MW:
251.23
Product Categories:
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Pyrrolidines
Mol File:
203866-15-3.mol
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N-BOC-4,4-difluoro-L-proline Chemical Properties

Melting point:
120-124 °C
Boiling point:
340.4±42.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
3.06±0.40(Predicted)
form 
powder to crystal
color 
White to Light yellow to Light orange
optical activity
[α]22/D -69.0° in chloroform
CAS DataBase Reference
203866-15-3
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37
WGK Germany 
3
HS Code 
29339900
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N-BOC-4,4-difluoro-L-proline Usage And Synthesis

Chemical Properties

solid

Uses

N-Boc-4,4-difluoro-L-proline is a reagent used in the preparation of structure-activity relationship and pharmacokinetics of pyrrolotriazines as pan-Aurora kinase inhibitors and anti tumor agents.

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