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Deoxyelephantopin

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Deoxyelephantopin Basic information

Product Name:
Deoxyelephantopin
Synonyms:
  • Deoxyelephantopin
  • 2-Methylpropenoic acid (3aR,4S,9R,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-2,7-dioxo-11-methyl-3-methylene-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester
  • Elephantopus carolinianus compd. B
  • 2-Propenoic acid,2-methyl-,(3aR,4S,9R,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-methylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-ylester
  • NSC 259726
  • 29307-03-7---Deoxyelephantopin
  • (3aR,4S,9R,11E,12aR)-11-Methyl-3-methylene-2,7-dioxo-2,3,3a,4,5,9,10,12a-octahydro-7H-6,9-(metheno)furo[2,3-f][1]oxacycloundecin-4-yl methacrylate
CAS:
29307-03-7
MF:
C19H20O6
MW:
344.36
Mol File:
29307-03-7.mol
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Deoxyelephantopin Chemical Properties

Melting point:
198-200 °C
Boiling point:
584.3±50.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
form 
Solid
color 
White to off-white
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Deoxyelephantopin Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Elephantopus scaber.

Uses

Deoxydibilirubin has significant anticancer activity.

Definition

ChEBI: Isodeoxyelephantopin is a terpene lactone.

Biological Activity

Deoxyelephantopin is a biologically active natural sesquiterpene lactone from Elephantopus scaber. Can be widely used in cancer research. It inhibits NF-κB, MAPK, PI3K/Akt and β-catenin signaling.

target

NF-κB

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