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INSULIN

Basic information Safety Supplier Related

INSULIN Basic information

Product Name:
INSULIN
Synonyms:
  • 8a-l-threonine-10a-l-isoleucine-insulin(ox
  • insulin(dog)
  • insulin(pig)
  • insulin(spermwhale)
  • insulin,neutral
  • insulinprocine
  • neutralinsulin
  • Insulin from porcine pancreas, ≥27 USP units/mg(HPLC)
CAS:
12584-58-6
MF:
C256H381N65O76S6
MW:
5777.54
EINECS:
235-703-3
Product Categories:
  • Insulin Signaling
Mol File:
Mol File
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INSULIN Chemical Properties

storage temp. 
-20°C
solubility 
It can be solubilized in dilute acetic or hydrochloric acid, pH 2-3.
form 
powder
color 
White to Off-White
Merck 
13,5003
Stability:
Hygroscopic
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NM8895000
10
HS Code 
2937120000
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INSULIN Usage And Synthesis

Chemical Properties

White or almost white powder

Uses

Insulin, from porcine pancreas, is used in the determination of the beta-cell reserve during glucose tolerance test or after a carbohydrate rich meal, as a guide for the instauration of insulin therapy, contribution to the diagnosis of insulin and non-insulin-dependent diabetes, characterisation and follow-up of states of glucose intolerance, diagnosis and study of cases of insulin resistance, diagnosis of insulinoma and other causes of hypoglycemia.

Uses

Hormone; treatment of diabetes mellitus.

Biological Functions

Insulin has anabolic properties that include the stimulation of both skeletal muscle and liver cells to incorporate glucose and convert it to glycogen, to synthesize proteins from amino acids in the blood, and to act on fat cells to enhance their uptake of glucose and the synthesis of fat. In short, insulin encourages anabolism rather than catabolism, because it promotes the synthesis of glycogen, proteins, and lipids. A deficiency of insulin, which characterizes the disease diabetes mellitus (DM), causes extreme changes in the entire metabolic pattern of individuals with DM. Patients with DM often demonstrate elevated blood glucose levels, excess glucose in the urine, and failure to properly utilize carbohydrate and lipids.

Biochem/physiol Actions

Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

INSULINSupplier

Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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sales@meilune.com
ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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shyysw007@163.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 18521732826;
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market@aladdin-e.com
The future of Shanghai Industrial Co., Ltd.
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021-61552785
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sales@shshiji.com
Sigma-Aldrich
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021-61415566 800-8193336
Email
orderCN@merckgroup.com