[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone Chemical Properties

storage temp. 

2-8°C

solubility 

DMSO: soluble10mg/mL, clear

form 

powder

color 

white to beige

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

WGK Germany 

3

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone Usage And Synthesis

Uses

ML-289 is a novel CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) NAM probe derived from mGlu5 PAM (1).

IC 50

mGluR3: 0.66 μM (IC₅₀)

storage

+4°C

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone(1382481-79-9)Related Product Information

• 5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinamine hydrochloride
• ML115
• ML246
• ML291
• 5-[6-(4-Methoxyphenyl)pyrazolo[1,5-a]
• ML318
• ML349
• ML355
• ML198
• ML402
• 1-(4-(4-(benzo[d][1,3]dioxole-5-carbonyl)piperazin-1-yl)phenyl)ethan-1-one
• 2-(3,4-dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide
• ML-228
• ML-098
• Nodinitib-1
• 9-Azabicyclo[3.3.1]nonane-9-acetamide, N-(2-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]-, (3-exo)-