ML-228 Chemical Properties

Boiling point:

686.0±65.0 °C(Predicted)

Density 

1.228±0.06 g/cm3(Predicted)

storage temp. 

-20°C, Inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

2.03±0.63(Predicted)

color 

Pale Yellow to Light Yellow

ML-228 Usage And Synthesis

Uses

N-([1,1''-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine is an activator of the hypoxia inducible factor (HIF) pathway.

Definition

ChEBI: ML228 is a member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. It has a role as a hypoxia-inducible factor pathway activator. It is a member of biphenyls, a member of 1,2,4-triazines, a secondary amino compound and a member of pyridines.

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