S-acetyl-PEG4-alcohol CAS#: 223611-42-5

S-acetyl-PEG4-alcohol Basic information

Product Name:

S-acetyl-PEG4-alcohol

Synonyms:

S-acetyl-PEG4-alcohol
S-acetyl-PEG4-OH
AcS-PEG4-OH
Ethanethioic acid, S-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl] ester
S-acetyl-dPEG??-OH
S-11-hydroxy-3,6,9-trioxaundecylethanethioate
Ac-s-teg-oh
S-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethyl) ethanethioate

CAS:

223611-42-5

MF:

C10H20O5S

MW:

252.33

Product Categories:

peg

Mol File:

223611-42-5.mol

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S-acetyl-PEG4-alcohol Chemical Properties

form: liquid
color: Clear

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Safety Information

HS Code: 2942000090

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S-acetyl-PEG4-alcohol Usage And Synthesis

Description

S-acetyl-PEG4-alcohol is a PEG linker containing a sulfur acetyl group which can be deprotected to form thiol groups. The hydroxyl group can undergo various reactions to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

S-acetyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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