Basic information Safety Supplier Related

(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL

Basic information Safety Supplier Related

(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL Basic information

Product Name:
(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL
Synonyms:
  • GITOGENIN
  • DIGIN
  • (25R)-2α,3β-Dihydroxy-5α-spirostan
  • (25R)-2α,3β-Dihydroxy-5α-spirostane
  • (2alpha,3beta,5alpha,25R)-Spirostan-2,3-diol
  • 2alpha-Hydroxytigogenin
  • (25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL
  • NSC 147752
CAS:
511-96-6
MF:
C27H44O4
MW:
432.64
Mol File:
511-96-6.mol
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(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL Chemical Properties

Melting point:
272-273℃
alpha 
D20 -75° (c = 1.02 in CHCl3)
Boiling point:
466.26°C (rough estimate)
Density 
1.16
refractive index 
1.4840 (estimate)
solubility 
Chloroform: 30 mg/ml
form 
A solid
pka
14.62±0.70(Predicted)
color 
White to off-white
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(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL Usage And Synthesis

Chemical Properties

Powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ophiopogon japonicus, Saposhnikovia divaricata, Fenugreek root, Tribulus terrestris root, and Giant fish maw flower.

Uses

Gitogenin is isolated from a methanolic extract of the whole plant of Tribulus longipetalus which exhibits inhibitory activities against α-glucosidase, lipoxygenase, acetylcholinesterase and butyrylcholinesterase.

Definition

ChEBI: Gitogenin is a triterpenoid.

in vivo

Stimulation of growth hormone release is investigated on rat pituitary cells in vitro. Gitogenin (20 μg/mL) shows rat growth-hormone (rGH) release stimulating activities (26.1 ng/mL)[3].

(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOLSupplier

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