(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL
(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL Basic information
- Product Name:
- (25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL
- Synonyms:
-
- GITOGENIN
- DIGIN
- (25R)-2α,3β-Dihydroxy-5α-spirostan
- (25R)-2α,3β-Dihydroxy-5α-spirostane
- (2alpha,3beta,5alpha,25R)-Spirostan-2,3-diol
- 2alpha-Hydroxytigogenin
- (25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL
- NSC 147752
- CAS:
- 511-96-6
- MF:
- C27H44O4
- MW:
- 432.64
- Mol File:
- 511-96-6.mol
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(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL Chemical Properties
- Melting point:
- 272-273℃
- alpha
- D20 -75° (c = 1.02 in CHCl3)
- Boiling point:
- 466.26°C (rough estimate)
- Density
- 1.16
- refractive index
- 1.4840 (estimate)
- solubility
- Chloroform: 30 mg/ml
- form
- A solid
- pka
- 14.62±0.70(Predicted)
- color
- White to off-white
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(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL Usage And Synthesis
Chemical Properties
Powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Ophiopogon japonicus, Saposhnikovia divaricata, Fenugreek root, Tribulus terrestris root, and Giant fish maw flower.
Uses
Gitogenin is isolated from a methanolic extract of the whole plant of Tribulus longipetalus which exhibits inhibitory activities against α-glucosidase, lipoxygenase, acetylcholinesterase and butyrylcholinesterase.
Definition
ChEBI: Gitogenin is a triterpenoid.
in vivo
Stimulation of growth hormone release is investigated on rat pituitary cells in vitro. Gitogenin (20 μg/mL) shows rat growth-hormone (rGH) release stimulating activities (26.1 ng/mL)[3].
(25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOLSupplier
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