BENZANILIDE Chemical Properties

Melting point:

161-163 °C(lit.)

Boiling point:

117 °C10 mm Hg(lit.)

Density 

1,315 g/cm³

refractive index 

1.6050 (estimate)

Flash point:

117°C/10mm

storage temp. 

Store below +30°C.

solubility 

H2O: insoluble

pka

13.52±0.70(Predicted)

Colour Index 

42095

form 

Powder

color 

Grayish to yellow-green

Water Solubility 

Insoluble

Merck 

14,1061

BRN 

1102980

CAS DataBase Reference

93-98-1(CAS DataBase Reference)

NIST Chemistry Reference

N-Phenylbenzoic acid amide(93-98-1)

EPA Substance Registry System

Benzanilide (93-98-1)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

TSCA 

Yes

HS Code 

29242990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

BENZANILIDE Usage And Synthesis

Chemical Properties

greyish to yellow-green powder

Uses

Benzanilide is used to make dyes, active pharmaceutical ingredients and perfumes. It is also used to study the influence of beta-cyclodextrin on photorearrangement of acetanilide, benzanilide and ethyl phenyl carbonate. Further, it is used as an amide model compound to study the reaction between the amide and epoxy. In addition to this, it reacts with aryltriflates in the presence of palladium-based catalyst system to get N-(2,6-diarylbenzoyl)anilines.

Uses

manufacture of dyes and perfumes.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 24, p. 187, 1987 DOI: 10.1002/jhet.5570240135
The Journal of Organic Chemistry, 20, p. 1482, 1955 DOI: 10.1021/jo01128a004
Tetrahedron Letters, 31, p. 1063, 1990 DOI: 10.1016/S0040-4039(00)94431-9

General Description

Benzanilide undergoes diarylation with aryl triflates or bromides in the presence of a palladium-based catalyst system to form corresponding N-(2,6-diarylbenzoyl)anilines. It is used in manufacture of dyes and perfumes.

Purification Methods

Crystallise benzanilide from pet ether (b 70-90o) using a Soxhlet extractor, and dry it overnight at 120o. Also crystallise it from EtOH. [Beilstein 12 IV 417.]

BENZANILIDE(93-98-1)Related Product Information

• XYLIDYL BLUE I SODIUM SALT
• Fast Blue BB
• NAPHTHOL AS ACETATE
• CI 37155
• N-(2,3-Dihydro-2-oxo-1H-benzimidazol-5-yl)-3-hydroxy-2-naphthalenecarboxamide
• BENZANILIDE
• FAST RED VIOLET LB BASE
• NAPHTHOL AS-BI PHOSPHATE
• 5-CHLOROSALICYLANILIDE
• N-Phenylbenzohydroxamic acid
• Salicylanilide
• Phthalylsulfathiazole
• CHLORANTINE FAST RED 5B
• 6(5H)-Phenanthridone
• Naphthol AS
• REACTIVE RED 4
• FAST RED VIOLET LB SALT
• 3'-Aminobenzanilide