ALLOMATRINE Chemical Properties

Melting point:

106-107 ºC

Boiling point:

396.7±31.0 °C(Predicted)

Density 

1.16

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

9.47±0.20(Predicted)

color 

White to off-white

InChI

InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15+/m0/s1

InChIKey

ZSBXGIUJOOQZMP-KYEXWDHISA-N

SMILES

N12CCC[C@]3([H])[C@]1([H])[C@@]([H])([C@@]1([H])CCCC(=O)N1C3)CCC2

ALLOMATRINE Usage And Synthesis

Uses

Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].

target

Bcl-2/Bax | Caspase | Akt | ROS | NF-kB | CDK

References

[1] Long Pan, et al. Chemical Constituents of Alkaloids From the Bark of Sophora Japonica. Zhong Yao Cai. 2016 Sep;39(9):2027-9. PMID:30209906
[2] Seiichi Kobashi , et al. Antinociceptive Effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in Mice: Structure-Activity Relation Study of Matrine-Type Alkaloids. Biol Pharm Bull. 2002 Aug;25(8):1030-4. DOI:10.1248/bpb.25.1030

ALLOMATRINE(641-39-4)Related Product Information

• Bengenin
• L-Menthol
• Epristeride
• Mivacurium chloride
• Phentolamine mesilate
• Ginsenoside Rg3
• PLERIXAFOR
• SOPHORIDINE
• Dihydroartemisinin
• alpha-Dihydroartemisinin
• Cepharanthine
• Quercetin dihydrate
• Quercetin
• DHQHS 2
• Sophoridine