Sophoridine
Sophoridine Basic information
- Product Name:
- Sophoridine
- Synonyms:
-
- I-SOPHORIDINE
- DIHYDRO-5-EPISOPHOCARPINE
- MATRIDIN-15-ONE
- 5-EPIDIHYDROSOPHOCARPINE
- (-)-SOPHORIDINE
- SOPHORIDINE
- SOPHORIDINE(RG)
- Matridin-15-one, (6β,7β,11α)- (9CI)
- CAS:
- 83148-91-8
- MF:
- C15H24N2O
- MW:
- 248.36
- Product Categories:
-
- Inhibitors
- Mol File:
- 83148-91-8.mol
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Sophoridine Chemical Properties
- Melting point:
- 108-9°C
- Boiling point:
- 396.7±31.0 °C(Predicted)
- Density
- 1.16±0.1 g/cm3(Predicted)
- solubility
- Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 9.47±0.20(Predicted)
- color
- Pale Yellow
- CAS DataBase Reference
- 83148-91-8
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Sophoridine Usage And Synthesis
Description
One of a number of minor alkaloids isolated from Leontice albertii Rgl., this base crystallizes from petroleum ether as colourless prisms. It is dextrorotatory having a specific rotation of [α]D + 59.3° (c 1.3, EtOH) and yields a crystalline methiodide, m.p. 249°C. The structure has been assigned on the basis of chemical analysis and spectroscopic determinations.
Uses
(+)-Sophoridine acts as an anti-inflammatory agent in vitro and in vivo. Anticancer agent, with a promising anti-tumor effect and lower toxicity.
References
Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967)
Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969)
SophoridineSupplier
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