Sophoridine Chemical Properties

Melting point:

108-9°C

Boiling point:

396.7±31.0 °C(Predicted)

Density 

1.16±0.1 g/cm3(Predicted)

solubility 

Chloroform (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

pka

9.47±0.20(Predicted)

color 

Pale Yellow

InChI

InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12-,13-,15+/m0/s1

InChIKey

ZSBXGIUJOOQZMP-PWNZVWSESA-N

SMILES

O=C1CCC[C@]2([H])N1C[C@]1([H])CCCN3CCC[C@]2([H])[C@@]13[H]

CAS DataBase Reference

83148-91-8

Sophoridine Usage And Synthesis

Description

One of a number of minor alkaloids isolated from Leontice albertii Rgl., this base crystallizes from petroleum ether as colourless prisms. It is dextrorotatory having a specific rotation of [α]_D + 59.3° (c 1.3, EtOH) and yields a crystalline methiodide, m.p. 249°C. The structure has been assigned on the basis of chemical analysis and spectroscopic determinations.

Chemical Properties

It is easily soluble in water, methanol, ethanol, carbon tetrachloride, etc. It is derived from the aerial parts of the leguminous plant Sophora alopecuroides L.

Uses

(+)-Sophoridine acts as an anti-inflammatory agent in vitro and in vivo. Anticancer agent, with a promising anti-tumor effect and lower toxicity.

in vivo

References

Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967)
Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969)

Sophoridine(83148-91-8)Related Product Information

• Ammothamnine
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• phellodendrine
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• Sophoricoside
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• Colchicine
• Silibinin
• HARRINGTONINE(P)
• Bupivacaine
• Berberine
• Betaine
• Puerarin
• ALOPERINE
• (-)-Sophoridine N-oxide,Sophoridine N-oxide