Sophoricoside Chemical Properties

Melting point:

298°

alpha 

D20 -47° (pyridine); D20 -32° (10% aq pyridine)

Boiling point:

466.08°C (rough estimate)

Density 

1.3597 (rough estimate)

refractive index 

1.5376 (estimate)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Aqueous Base (Slightly), DMSO (Slightly, Heated), Pyridine (Slightly, Sonicated)

pka

6.45±0.20(Predicted)

form 

Solid

color 

White to Light Brown

λmax

271nm(MeOH)(lit.)

CAS DataBase Reference

152-95-4(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

HS Code 

29329990

Sophoricoside Usage And Synthesis

Chemical Properties

Light yellow solid

Uses

Genistein 4''-β-D-glucopyranoside is a metabolite of Genistein (G350000), which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation.

Definition

ChEBI: Sophoricoside is an isoflavonoid and an acrovestone.

Biological Activity

Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-KB) pathway in B cells in mice model.', 'Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities. It inhibits proinflammatory cytokine production in human mast cells and has the potential to tre at allergic inflammation diseases.

Sophoricoside(152-95-4)Related Product Information

• SOPHORIDINE
• Sophoridine
• Tea polyphenol
• Naringin
• Ginkgo biloba extract
• Polydatin
• Evodiamine
• PINOCEMBRIN
• CALYCOSIN
• Quercetin dihydrate
• Rotundine
• Tris(hydroxymethyl)nitromethane
• Solvent Red 43
• Tangeretin
• Genistein
• 5,7-DIHYDROXYISOFLAVONE
• 5,4'-DIHYDROXY-7-METHOXYISOFLAVONE-4'-O-GLUCOSIDE
• Sophoricoside