Sophocarpine Monohydrate Chemical Properties

Melting point:

8l-2°C

storage temp. 

-20°C Freezer

solubility 

Acetone; Dichloromethane

form 

Solid

color 

Pale brownish

Safety Information

HS Code 

2939.80.0000

Sophocarpine Monohydrate Usage And Synthesis

Description

A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20 as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has [α]¹⁸_D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. > 300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride, m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base, ClsH26N2, b.p. l53-4°C/5 mm; [α]_D - 26.2° (EtOH) and giving a methiodide with a melting point above 300°C. Attempted degradation by the Hofmann process has proved unsuccessful.

Chemical Properties

White needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Sophora flavescens, a plant of the genus Macleaya in the Papaveraceae family.

Uses

Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of this compound results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis.

IC 50

PI3K

References

Orekhov, Proskurnina., Ber., 67,77 (1934)
Proskurnina, Kuzuvkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)

Sophocarpine Monohydrate(145572-44-7)Related Product Information

• Ammothamnine
• Matrine
• Sophocarpine
• phellodendrine
• CHELIDONINE
• Tannic acid berberine
• Resveratrol
• Gallic acid monohydrate
• Wogonin
• D-Tetrandrine
• Yohimbine hydrochloride
• Ursolic acid
• lithospermic acid B
• Coptisine chloride
• (+)-Camptothecin
• Sophoridine
• CYTISINE
• Lycorine hydrochloride