(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate Chemical Properties

Boiling point:

484.2±45.0 °C(Predicted)

Density 

1.12±0.1 g/cm3(Predicted)

pka

7.76±0.10(Predicted)

(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate Usage And Synthesis

Uses

Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].

Definition

ChEBI: Propiverine is a diarylmethane.

References

[1] McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33(1):71-91. DOI:10.1007/s40261-012-0046-9
[2] Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic). World J Urol. 2001 Nov;19(5):324-35. DOI:10.1007/s003450100223

(1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate(60569-19-9)Related Product Information

• Sodium acetate
• Methyl acetate
• Triacetonediamine
• Ammonium acetate
• Glatiramer acetate
• Biphenyl
• Chlorodiphenylphosphine
• Ethyl acetate
• 2,2,6,6-Tetramethyl-4-piperidinol
• Cellulose acetate
• tert-Butylchlorodiphenylsilane
• Vinyl acetate
• Ethyl propionylacetate
• 2-METHYL-1,3-PROPANEDIOL
• Propiverine hydrochloride
• ACETATE
• Benzilic acid
• (S)-(+)-alpha-Methoxyphenylacetic acid