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Cefozopran hydrochloride

Basic information Safety Supplier Related

Cefozopran hydrochloride Basic information

Product Name:
Cefozopran hydrochloride
Synonyms:
  • Cefozopran hydrochloride
  • (6R,7R)-7-[[(2E)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride
  • Cefozopran hydrochloride (jp15)
  • Czop
  • D02233
  • Firstcin (tn)
  • Cefozopran hydrochlo
  • SCE-2787 hydrochloride
CAS:
113981-44-5
MF:
C19H18ClN9O5S2
MW:
551.98
EINECS:
1806241-263-5
Product Categories:
  • Cefozopran Hydrochloride and its intermediates
Mol File:
113981-44-5.mol
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Cefozopran hydrochloride Chemical Properties

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
Solid
color 
White to light yellow
Water Solubility 
Water : ≥ 52 mg/mL (94.20 mM)
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Cefozopran hydrochloride Usage And Synthesis

Antimicrobial activity

Cefazolam hydrochloride is suitable for Staphylococcus, Streptococcus, Enterococcus, Peptostreptococcus, Escherichia coli, Enterobacter, Serratia, Klebsiella, Citrobacter, Proteus, Pseudomonas, Influenza Bacillus, Acinetobacter, Bacteroidetes, septicemia caused by sensitive bacteria to cefazolam hydrochloride, trauma infection, respiratory system, urinary system and abdominal cavity, pelvic purulent inflammation, ophthalmology and ENT inflammation, etc.

Biological Activity

Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. As an antibiotic, it has broad-spectrum antibacterial activity and can inhibit most Gram-negative and Gram-positive bacteria.

in vitro

Cefozopran (SCE-2787) is a fourth-generation cephalosporin that has good activity against gram-positive organisms including methicillin-susceptible staphylococci, enterococci, and viridans group streptococci; and against gram-negative organisms including hemophilus influenza. Moreover, cefozopran has comparatively good activity against enterococci and P. aeruginosa , which are refractory to other cephalosporins.

in vivo

Cefozopran (SCE-2787) (5-80 mg/kg; sc; twice a day for 5 days; four-week-old ICR male mice) is effective against acute respiratory tract infections caused by Kiebsiella pneumonia DT-S. In the model of chronic respiratory tract infection caused by K. pneumoniae 27, Cefozopran (20-80 mg/kg; sc; twice a day for 7 days; five-week-old CBA/J female mice) is as effective as Ceftazidime.

Cefozopran hydrochlorideSupplier

JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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sales@jingyan-chemical.com
Shanghai Ennopharm Co., Ltd.
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+86 (21) 6435-5022
Hangzhou Yuhao Chemical Technology Co., Ltd
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0571-82693216
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info@yuhaochemical.com
Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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meilunui@163.com
BioBioPha Co., Ltd.
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0871-65217109 13211707573;
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y.liu@mail.biobiopha.com