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luteolin-7-glucuronide

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luteolin-7-glucuronide Basic information

Product Name:
luteolin-7-glucuronide
Synonyms:
  • Luteolin-7-beta-D-glucuronide
  • Luteolin 7-O-beta-D-glucuronopyranoside
  • Luteolin 7-O-beta-glucuronide
  • Luteolin 7-O-beta-glucuronopyranoside
  • b-D-Glucopyranosiduronic acid,2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-1-benzopyran-7-yl
  • Luteolin-7-O-glucuronide
  • 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid
  • 3′,4′,5,7-Tetrahydroxy-7-β-D-glucopyranuronoside flavone
CAS:
29741-10-4
MF:
C21H18O12
MW:
462.36
Product Categories:
  • Miscellaneous Natural Products
Mol File:
29741-10-4.mol
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luteolin-7-glucuronide Chemical Properties

Melting point:
242-244℃
Boiling point:
892.5±65.0 °C(Predicted)
Density 
1.810±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
2.73±0.70(Predicted)
color 
Pale Yellow to Light Yellow
Stability:
Hygroscopic
InChIKey
VSUOKLTVXQRUSG-DAZJWRSOSA-N
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Safety Information

WGK Germany 
3
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luteolin-7-glucuronide Usage And Synthesis

Chemical Properties

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from bitter dish.

Uses

Luteolin- 7-?O-Glucuronide is a compound displaying strong anti-oxidant activity.

Definition

ChEBI: A luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 7-position.

in vivo

Luteolin 7-O-glucuronide (0.3-3 mg/kg, p.o., once daily for 5 days) improves depression-like and stress coping behaviors in the tail suspension test and forced swimming test in a mouse sleep deprivation model[3].

Animal Model:mouse sleep deprivation model[3]
Dosage:0.3-3 mg/kg
Administration:p.o., once daily for 5 days
Result:Reduced the increased immobility time in sleep-deprived mice.
Reduced the increased plasma corticosterone level.
Reduced TNF-α and IL-1β level and increased BDNF mRNA expression in the hippocampus of sleep-deprived mice.

IC 50

MMP-1: 17.63 μM (IC50); MMP-3: 7.99 μM (IC50); MMP-8: 11.42 μM (IC50); MMP-9: 12.85 μM (IC50); MMP13: 0.03 μM (IC50)

luteolin-7-glucuronideSupplier

Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Email
cwb1@biopurify.cn
Shanghai Winherb Medical Technology Co., Ltd.
Tel
021-38218169 13341702378
Email
winherb@126.com
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Email
marketing@targetmol.com
Chengdu Herbpurify Co.Ltd.
Tel
2355253622; 18981954830
Email
2355253622@qq.com;
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luteolin-7-glucuronide(29741-10-4)Related Product Information