- Product Name:
- DISILANE M6
- Product Categories:
- organosilicon compounds
- Pharmaceutical Intermediates
- Blocking Agents
- Protective Agents
- Chemical Synthesis
- Organometallic Reagents
- Standards for NMR
- Silylating Agents
- Special Silanes
- DisilanesVapor Deposition Precursors
- Organometallic Reagents
- Precursors by Metal
- Analytical Chemistry
- NMR Spectrometry
- Si (Classes of Silicon Compounds)
- Silicon Compounds (for Synthesis)
- Si-Si Compounds
- Synthetic Organic Chemistry
- Mol File:
Hexamethyldisilane Chemical Properties
- Melting point:
- 9-12 °C (lit.)
- Boiling point:
- 112-114 °C (lit.)
- 0.715 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.422(lit.)
- Flash point:
- 29 °F
- storage temp.
- Store at <= 20°C.
- sol common organic solvents; insol H2O.
- Specific Gravity
- Water Solubility
- Insoluble in water. Soluble in alcohol, ether and acetone.
- Hydrolytic Sensitivity
- 1: no significant reaction with aqueous systems
- CAS DataBase Reference
- 1450-14-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Disilane, hexamethyl-(1450-14-2)
- EPA Substance Registry System
- Disilane, hexamethyl- (1450-14-2)
Hexamethyldisilane Usage And Synthesis
Colorless clear liquid
Hexamethyldisilane acts as a silylating reagent for allylic acetates, aryl halides and diketones. It is a source material for vapor deposition during silicon carbide growth. It is also used in electronic and semiconducter industries.
Hexamethyldisilane is an important silane protective agent, which can synthesize sodium trimethylsilane, potassium trimethylsilane and lithium trimethylsilane.
Preparation of iodotrimethylsilane.
Used as trimethylsilane anion reagent.
silylating or reducing reagent in combination with a Pd catalyst or a nucleophile.
Replaces aromatic nitriles with TMS groups in presence of [RhCl(cod)]2.
Precursor for CVD of silicon carbide.
Brings about the homocoupling of arenesulfonyl chlorides in the presence of Pd2(dba)3.
Used as a solvent for the direct borylation of fluoroaromatics.
Reacts with alkynes to form siloles.
Undergoes the silylation of acid chlorides to give acylsilanes.
Hexamethyldisilane is produced by the reaction of methyl Grignard reagent with methylchlorodisilanes. This reaction is normally conducted in the presence of an ether such as diethyl ether, ethyl propyl ether, THF and the like.
Hexamethyldisilazane (HMDZ) is a highly flammable liquid and vapour.
HMDZ liquid is lighter than water and may float on water, spreading material during fire fighting. Leaking material or fire runoff to sewer may create fire or explosion hazard.
HMDZ vapours are heavier than air and can accumulate to form explosive concentrations. The vapours may also spread a considerable distance to a source of ignition, and flash back towards the source.
HMDZ reacts with water to form ammonia.
HMDZ is a non-conductor and, therefore, can accumulate static electrical charges when processed, handled or dispensed. HMDZ's flash point is 52 to 53°F, closed cup, for "pure" material.
The most likely impurity is trimethylchlorosilane (cf boiling point). Wash it with H2O, cold conc H2SO4, H2O again, then aqueous NaHCO3, dry over CaSO4 and fractionate at atmospheric pressure. [Brown & Fowles J Chem Soc 2811 1958.] A grossly impure sample (25% impurities) was purified by repeated spinning band distillation. This lowered the impurity level to 500ppm. The main impurity was identified as 1-hydroxypentamethyldisilane. [Beilstein 4 IV 4277.]
- 021-33516722 13701817765
- 0514-85083918 13056321938
- 010-82848833 400-666-7788
- Lithium bis(trimethylsilyl)amide
- tert-Butyldimethylsilyl chloride
- SALOR-INT L170682-1EA
- Bis(2-methoxyphenyl)-1,1,2,2-tetramethyldisilane, 95%