1-BROMO-2,4-DIFLUORO-5-NITROBENZENE Chemical Properties

Melting point:

19°C(lit.)

Boiling point:

85°C 0,4mm

Density 

1.890±0.06 g/cm3(Predicted)

refractive index 

1.5580 to 1.5620

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to lump to clear liquid

color 

White or Colorless to Light yellow

CAS DataBase Reference

345-24-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HazardClass 

IRRITANT

HS Code 

2904990090

1-BROMO-2,4-DIFLUORO-5-NITROBENZENE Usage And Synthesis

Uses

1-Bromo-2,4-difluoro-5-nitrobenzene is a nitrobenzene derivative containing fluorine and bromine atom substituents. It can be used as a pharmaceutical intermediate for the preparation of novel N2-phenylpyrimidine-2,4-diamine compounds showing effective inhibition of EGFR mutations, and thus can be effectively used in the treatment of EGFR-mutated cancers.

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