ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyran compounds > 6,7,8-TRIMETHOXYCOUMARIN
6,7,8-TRIMETHOXYCOUMARIN
6,7,8-TRIMETHOXYCOUMARIN Basic information
- Product Name:
- 6,7,8-TRIMETHOXYCOUMARIN
- Synonyms:
-
- O,O-DIMETHYLFRAXETIN
- 6,7,8-TRIMETHOXYCOUMARIN
- DIMETHYLFRAXETIN, O,O-(RG)
- DIMETHYLFRAXETIN
- DIMETHYLFRAXETIN, O,O-
- 6,7,8-Trimethoxy-2H-1-benzopyran-2-one
- Di-O-Methylfraxetin
- Fraxetin dimethyl ether
- CAS:
- 6035-49-0
- MF:
- C12H12O5
- MW:
- 236.22
- EINECS:
- 200-485-9
- Product Categories:
-
- Coumarins
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 6035-49-0.mol
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6,7,8-TRIMETHOXYCOUMARIN Chemical Properties
- Melting point:
- 104-105°C
- Boiling point:
- 338.68°C (rough estimate)
- Density
- 1.249
- refractive index
- 1.5140 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming)
- form
- Cryst.
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6,7,8-TRIMETHOXYCOUMARIN Usage And Synthesis
Chemical Properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.
Uses
Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.
Definition
ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.
Biological Activity
Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.
in vitro
At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .
target
Ki: 0.0097 μM (Carbonic anhydrase)
6,7,8-TRIMETHOXYCOUMARINSupplier
Shanghai YuanYe Biotechnology Co., Ltd. Gold
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Chembest Research Laboratories Limited
- Tel
- 021-20908456
- sales@BioChemBest.com
BEST-REAGENT
- Tel
- 400-1166-196 18981987031
- cdhxsj@163.com
Shenzhen Sungening Bio-Tech Co., Ltd
- Tel
- +86-0755-89668383
- sales@sungening.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
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6,7,8-TRIMETHOXYCOUMARIN(6035-49-0)Related Product Information
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- 7,8-DIHYDROXY-6-METHOXYCOUMARIN
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- 8-HYDROXY-7-METHOXYCOUMARIN
- 6,7,8-TRIMETHOXYCOUMARIN
- Isofraxidin
- 2,3-Dimethoxy-5-methyl-1,4-hydroquinone
- 6-HYDROXY-7-METHOXYCOUMARIN
- 2,3,4-Trimethoxy-6-methylphenol
- FRAXIDIN
- SCOPARONE
- 1,2,3,4-TETRAMETHOXYBENZENE
- 5,6,7-Trimethoxycoumarin
- 2,3-DIMETHOXYHYDROQUINONE
- DAPHNETIN
- 7,8-dimethoxycoumarin
- 1-ALLYLOXY-2-METHOXY-BENZENE