Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyran compounds >  6,7,8-TRIMETHOXYCOUMARIN

6,7,8-TRIMETHOXYCOUMARIN

Basic information Safety Supplier Related

6,7,8-TRIMETHOXYCOUMARIN Basic information

Product Name:
6,7,8-TRIMETHOXYCOUMARIN
Synonyms:
  • O,O-DIMETHYLFRAXETIN
  • 6,7,8-TRIMETHOXYCOUMARIN
  • DIMETHYLFRAXETIN, O,O-(RG)
  • DIMETHYLFRAXETIN
  • DIMETHYLFRAXETIN, O,O-
  • 6,7,8-Trimethoxy-2H-1-benzopyran-2-one
  • Di-O-Methylfraxetin
  • Fraxetin dimethyl ether
CAS:
6035-49-0
MF:
C12H12O5
MW:
236.22
EINECS:
200-485-9
Product Categories:
  • Coumarins
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
6035-49-0.mol
More
Less

6,7,8-TRIMETHOXYCOUMARIN Chemical Properties

Melting point:
104-105°C
Boiling point:
338.68°C (rough estimate)
Density 
1.249
refractive index 
1.5140 (estimate)
storage temp. 
2-8°C
solubility 
DMSO : 125 mg/mL (529.17 mM; Need ultrasonic and warming)
form 
Cryst.
color 
White to yellow
More
Less

Safety Information

Risk Statements 
22
Safety Statements 
22-45
HS Code 
29322090
More
Less

6,7,8-TRIMETHOXYCOUMARIN Usage And Synthesis

Chemical Properties

White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.

Uses

Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.

Definition

ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.

Biological Activity

Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.

in vitro

At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .

target

Ki: 0.0097 μM (Carbonic anhydrase)

6,7,8-TRIMETHOXYCOUMARINSupplier

Shanghai YuanYe Biotechnology Co., Ltd. Gold
Tel
021-61312847; 18021002903
Email
3008007409@qq.com
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Email
sales@BioChemBest.com
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Email
cdhxsj@163.com
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Email
sales@sungening.com
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
More
Less

6,7,8-TRIMETHOXYCOUMARIN(6035-49-0)Related Product Information