ISOPROPYLMAGNESIUM BROMIDE Chemical Properties

Melting point:

114-116℃

Boiling point:

148-154℃

Density 

0.982 g/mL at 25 °C

Flash point:

-17°C

storage temp. 

2-8°C

solubility 

Miscible with tetrahydorfuran and diethyl ether. Immiscible with hydrocarbons.

form 

Solution

color 

Clear dark brown or dark gray

Sensitive 

Air & Moisture Sensitive

InChI

InChI=1S/C3H7.BrH.Mg/c1-3-2;;/h3H,1-2H3;1H;/q;;+1/p-1

InChIKey

UCJIVFREPMUZDC-UHFFFAOYSA-M

SMILES

C(C)(C)[Mg]Br

EPA Substance Registry System

Magnesium, bromo(1-methylethyl)- (920-39-8)

Safety Information

Hazard Codes 

F,C

Risk Statements 

11-19-34-14/15-40-37-17-14

Safety Statements 

16-26-27-36/37/39-45-43-39-37-36

RIDADR 

3399

WGK Germany 

2

TSCA 

TSCA listed

HazardClass 

4.3

PackingGroup 

I

HS Code 

29319090

Storage Class

4.3 - Hazardous materials which set free flammable gases upon contact with water

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 2
Skin Corr. 1B
Water-react 2

ISOPROPYLMAGNESIUM BROMIDE Usage And Synthesis

Chemical Properties

Clear dark brown or dark gray solution

Uses

Isopropylmagnesium bromide is a Grignard reagent used in organic synthesis, especially for the introduction of iso-propyl group to carbonyl compounds. It is also used as a strong base in aprotic solvent.

Uses

Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF)

2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

General Description

This product, 2.9 M in 2-methyltetrahydrofuran aligns with Safer Solvents and Auxiliaries, Use of Renewable Feedstocks and Inherently Safer Chemistry for Accident Prevention.

reaction suitability

reaction type: Grignard Reaction

Synthesis

Nitrogen was replaced 3 times in a 500L reactor, 25.25kg of magnesium balls (0.8cm) were added, 100L of 2-methyltetrahydro was added and the initiator (2-bromopropane Grignard reagent) was 2kg. furan and initiator (2-bromopropane Grignard reagent) 2kg, heated to 60-65 degrees reflux, slowly at 50-60 degrees dropwise addition of 123kg of 2- bromopropane and 120L of 2-methyltetrahydrofuran mixture, to make a clear and transparent light brown to light gray liquid, dropwise addition is completed . reflux for 2 hours, acid-base titration concentration of 3.02 mol, reduce the temperature to about 10 degrees Celsius, stationary settlement for 24 hours, a small amount of black suspension and precipitate deposited at the bottom of the reactor, and no other solid precipitation, the supernatant pressure into the cylinder.

ISOPROPYLMAGNESIUM BROMIDE(920-39-8)Related Product Information

• ISOBUTYLMAGNESIUM CHLORIDE
• ISOBUTYLMAGNESIUM BROMIDE
• Vinylmagnesium bromide
• N-PROPYLMAGNESIUM BROMIDE
• Methylmagnesium Bromide
• ETHYNYLMAGNESIUM BROMIDE
• 1-PROPENYLMAGNESIUM BROMIDE
• ISOPROPENYLMAGNESIUM BROMIDE
• Chloromethyl isopropyl carbonate
• Vinyl isopropyl ether
• Isobutaneboronic acid
• Aluminium isopropoxide
• ISOPROPYLMAGNESIUM CHLORIDE
• Diisopropyl ether
• Isopropylmagnesium chloride lithium chloride complex
• SEC-BUTYLMAGNESIUM BROMIDE
• CYCLOHEXYLMAGNESIUM BROMIDE
• Cyclopropylmagnesium bromide