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Parbendazole

Basic information Safety Supplier Related

Parbendazole Basic information

Product Name:
Parbendazole
Synonyms:
  • PARBENDAZOLE
  • (4-butyl-1h-benzimidazol-2-yl)-carbamicacidmethylester
  • (5-butyl-1h-benzimidazol-2-yl)-carbamicacimethylester
  • 5-butyl-2-benzimidazolecarbamicacimethylester
  • helmatac
  • methyl5-butyl-2-benzimidazolecarbamate
  • n-(butyl-5,benzimidazolyl)-2,carbamatedemethyle
  • pbdz
CAS:
14255-87-9
MF:
C13H17N3O2
MW:
247.29
EINECS:
238-133-3
Mol File:
14255-87-9.mol
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Parbendazole Chemical Properties

Melting point:
255-257°C
Boiling point:
390.33°C (rough estimate)
Density 
1.1214 (rough estimate)
refractive index 
1.5700 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka
11.66±0.10(Predicted)
color 
White to Off-White
Water Solubility 
<0.1 g/100 mL at 18 ºC
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
YRWLZFXJFBZBEY-UHFFFAOYSA-N
EPA Substance Registry System
Parbendazole (14255-87-9)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
63-22
Safety Statements 
36/37
WGK Germany 
3
RTECS 
DD6495000
HS Code 
2933997500
Toxicity
LD50 in mice, rats (g/kg): >4 orally, both species (Actor)

MSDS

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Parbendazole Usage And Synthesis

Chemical Properties

solid

Uses

Antiparasitic

Uses

Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.

Definition

ChEBI: N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester is a carbamate ester and a member of benzimidazoles.

General Description

Crystals or fine white powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Parbendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition Parbendazole emits toxic fumes.

Fire Hazard

Flash point data for Parbendazole are not available; however, Parbendazole is probably combustible.

ParbendazoleSupplier

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