3-Amino-5-phenylpyrazole Chemical Properties

Melting point:

124-127 °C (lit.)

Boiling point:

442.3±33.0 °C(Predicted)

Density 

1.238±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO, Methanol

pka

14.80±0.10(Predicted)

form 

Powder or Crystals

color 

Red to brown

BRN 

4947

InChIKey

PWSZRRFDVPMZGM-UHFFFAOYSA-N

CAS DataBase Reference

1572-10-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

RTECS 

UQ6109000

Hazard Note 

Irritant

HS Code 

29331990

Toxicity

mouse,LDLo,intraperitoneal,630mg/kg (630mg/kg),Farmakologiya i Toksikologiya Vol. 27, Pg. 295, 1964.

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-Amino-5-phenylpyrazole Usage And Synthesis

Chemical Properties

Off-white to cream colored crystalline powder

Uses

3-Amino-5-phenylpyrazole ((3-phenyl-1H-pyrazol-5-amine) may be used in the synthesis of the following:

• Urea derivatives by reaction with azido(6-(benzofuran-2-yl)-2-methylpyridin-3-yl) methanone.
• 2-Mercaptoacetamide analogs by treating with thioglycolic acid.
• 3-(Substituentpyrimidayl)-5,6-benzocoumarins by treating with 3-(2′-formyl-1′-chlorovinyl)-5,6-benzocoumarin.
• Substituted 2,7-diphenylpyrazolo[1,5-a]pyrimidine-5-carboxylic esters by reacting with substituted β-diketo esters.
• N-ethoxycarbonylthiourea derivative by reacting with ethoxycarbonyl isothiocyanate.
• Heterobiaryl pyrazolo[3,4-b]pyridines by reacting with indole-3-carboxaldehyde.

General Description

3-Amino-5-phenylpyrazole (3-phenyl-1H-pyrazol-5-amine), an amino pyrazole derivative, is an aza-heterocyclic amine. It has been reported to be synthesized by heating either 3-amino-4-bromo- or 3-amino-5-phenylisothiazole in the presence of anhydrous hydrazine. On reaction with ZnCl₂ it affords chlorido-tris(3-amino-5-phenyl-1Hpyrazole-N²)zinc (II) chloride.

3-Amino-5-phenylpyrazole(1572-10-7)Related Product Information

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