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Z-TLE-OH DCHA

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Z-TLE-OH DCHA Basic information

Product Name:
Z-TLE-OH DCHA
Synonyms:
  • 3-Methyl-N-[(phenylmethoxy)carbonyl]-L-valine compd. with N-cyclohexylcyclohexanamine
  • Z-L-tert-butyl-Gly-OH·DCHA
  • Z-L-Tle-OH·DCHA
  • (-)-N-Benzyloxycarbonyl-L-tert-leucine dicyclohexyl ammonium salt for synthesis
  • N-ALPHA-CARBOBENZOXY-L-ALPHA-T-BUTYLGLYCINE DICYCLOHEXYLAMINE SALT
  • N-ALPHA-CARBOBENZOXY-L-TERT-LEUCINE DICYCLOHEXYLAMINE SALT
  • (-)-N-BENZYLOXYCARBONYL-L-TERT-LEUCINE DICYCLOHEXYLAMMONIUM SALT
  • Z-ALPHA-T-BUTYL-GLY-OH DCHA
CAS:
62965-37-1
MF:
C14H19NO4.C12H23N
MW:
446.63
EINECS:
478-250-9
Mol File:
62965-37-1.mol
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Z-TLE-OH DCHA Chemical Properties

Melting point:
163-167 °C
Density 
1.1 at 20℃
vapor pressure 
0Pa at 25℃
storage temp. 
2-8°C
form 
Solid
PH
6.3 (H2O, 20℃)(saturated solution)
optical activity
[α]20/D 6.5±1°, c = 1% in methanol
BRN 
3831936
LogP
1.6 at 25℃ and pH2.5
Surface tension
63mN/m at 1g/L and 20℃
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10-21
HS Code 
2906190090

MSDS

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Z-TLE-OH DCHA Usage And Synthesis

Uses

3-methyl-N-[(phenylmethoxy)carbonyl]-L-Valine, with N-cyclohexylcyclohexanamine is used in the preparation of an intermediate towards the interleukin-1β converting enzyme inhibitor VX-765 using the palladium-catalyzed coupling of a bromodihydrofuranone with Cbz-L-prolinamide as the key step.

Z-TLE-OH DCHASupplier

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