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Diethyl (hydroxymethyl)phosphonate

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Diethyl (hydroxymethyl)phosphonate Basic information

Product Name:
Diethyl (hydroxymethyl)phosphonate
Synonyms:
  • AURORA KA-1421
  • DIETHYL HYDROXYMETHYLPHOSPHONATE
  • (Hydroxymethyl)phosphonic acid, diethyl ester
  • (hydroxymethyl)-phosphonicacidiethylester
  • Phosphonic acid, (hydroxymethyl)-, diethyl ester
  • 4-Hydroxymethyldiethylphosphonate
  • DIETHYL (HYDROXYMETHYL)PHOSPHONATE, TECH .
  • Diethyl Phosphonometanol
CAS:
3084-40-0
MF:
C5H13O4P
MW:
168.13
EINECS:
221-391-6
Product Categories:
  • C-C Bond Formation
  • Horner-Wadsworth-Emmons Reagents
  • Olefination
Mol File:
3084-40-0.mol
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Diethyl (hydroxymethyl)phosphonate Chemical Properties

Boiling point:
124-126 °C/3 mmHg (lit.)
Density 
1.14 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.444(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Viscous Liquid
pka
13.00±0.10(Predicted)
color 
Clear colorless to yellow
Water Solubility 
500g/L at 20℃
InChIKey
RWIGWWBLTJLKMK-UHFFFAOYSA-N
CAS DataBase Reference
3084-40-0(CAS DataBase Reference)
NIST Chemistry Reference
Diethyl hydroxymethylphosphonate(3084-40-0)
EPA Substance Registry System
Phosphonic acid, (hydroxymethyl)-, diethyl ester (3084-40-0)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-36-37
WGK Germany 
3
TSCA 
Yes
HS Code 
29319090

MSDS

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Diethyl (hydroxymethyl)phosphonate Usage And Synthesis

Chemical Properties

Clear colorless to yellow viscous liquid

Uses

Diethyl hydroxymethylphosphonate acts as a reactant for synthesis of α And β-dialkoxyphosphoryl isothiocyanate used in antiproliferative studies, dendritic polyglycerol anions for L-selectin inhibition, phosphonates for anti-HIV-1 activity, homo and copolymers of phosphonated norbornenes, Mitsunobu reactions. It is involved in studies of FBPase inhibition by phosphonic acid-containing thaizoles.

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