Dimethyl 5-hydroxyisophthalate Chemical Properties

Melting point:

162-164 °C (lit.)

Boiling point:

360.6±22.0 °C(Predicted)

Density 

1.284±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Powder and/or Lumps

pka

8.33±0.10(Predicted)

color 

White to light beige

Water Solubility 

Soluble in water.

BRN 

2650120

InChIKey

DOSDTCPDBPRFHQ-UHFFFAOYSA-N

LogP

2.570 (est)

CAS DataBase Reference

13036-02-7(CAS DataBase Reference)

EPA Substance Registry System

Dimethyl 5-hydroxyisophthalate (13036-02-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

TSCA 

Yes

HS Code 

29182900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Dimethyl 5-hydroxyisophthalate Usage And Synthesis

Chemical Properties

off-white crystal powder

Uses

Dimethyl 5-Hydroxyisophthalate is a useful synthetic intermediate in the synthesis of N,N?-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)carbamoyl)methoxy]-2,4,6-triiodoisophthalamide (B426310); a compound related to Ioversol( I737000) which is a nonionic, low osmolality, radiographic contrast agent.

General Description

Dimethyl 5-hydroxyisophthalate undergoes a base-catalyzed nucleophilic oxirane ring-opening addition reaction with allyl glycidyl ether, to afford 5-substituted derivatives of isophthalic acid. Influence of third component, i.e. a series of 1,ω-alkanediols on the copolymerization reaction of dimethyl 5-hydroxyisophthalate with poly(ethylene glycol) has been studied. Lipase-catalyzed condensation polymerization of dimethyl 5-hydroxyisophthalate with polyethylene glycol is reported.

Dimethyl 5-hydroxyisophthalate(13036-02-7)Related Product Information

• 2'-Hydroxy-3-phenylpropiophenone
• 2,3,4-Trihydroxybenzoic acid
• 5-Hydroxyisophthalic acid
• Dimethyl sulfoxide
• Dimethyl carbonate
• Dimethyl ether
• Dimethyl phthalate
• Dimethyl fumarate
• ETHANE
• Dimethyl isophthalate
• Dimethyl disulfide
• Dimethyl sulfate
• Dacthal
• Butylparaben
• Biphenyl dimethyl dicarboxylate
• Methylparaben
• Dimethyl terephthalate
• N,N-Dimethylformamide