2-Methoxy-5-methylaniline Chemical Properties

Melting point:

50-52 °C (lit.)

Boiling point:

235 °C (lit.)

Density 

1.0252 (rough estimate)

vapor density 

4.7 (vs air)

refractive index 

1.5647 (estimate)

Flash point:

>230 °F

storage temp. 

Room Temperature, under inert atmosphere

solubility 

Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)

form 

Crystalline Chunks

pka

4.66±0.10(Predicted)

color 

Brown to black

Water Solubility 

Slightly soluble in hot water.

BRN 

637071

Stability:

Air Sensitive

InChIKey

WXWCDTXEKCVRRO-UHFFFAOYSA-N

CAS DataBase Reference

120-71-8(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2-methoxy-5-methyl-(120-71-8)

IARC

2B (Vol. 27, Sup 7) 1987

EPA Substance Registry System

p-Cresidine (120-71-8)

Safety Information

Hazard Codes 

T,Xi

Risk Statements 

45-22

Safety Statements 

53-45

WGK Germany 

3

RTECS 

BZ6720000

F 

9

HazardClass 

IRRITANT

HS Code 

29222990

Hazardous Substances Data

120-71-8(Hazardous Substances Data)

MSDS

• Language:English Provider:2-Methoxy-5-methylaniline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-Methoxy-5-methylaniline Usage And Synthesis

Chemical Properties

brown to black crystalline chunks

Chemical Properties

p-Cresidine is a white crystalline solid.

Uses

p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides. Dyes and metabolites, Environmental Testing.

Uses

2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase.

Uses

p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides.

General Description

White to silver-gray odorless crystals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Methoxy-5-methylaniline is sensitive to moisture and temperatures greater than 104°F. Incompatible with strong oxidizing agents .

Hazard

A possible carcinogen.

Fire Hazard

2-Methoxy-5-methylaniline is nonflammable.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Moderately toxic by ingestion. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.

Potential Exposure

p-Cresidine is used as an intermediate in the production of various azodyes, printing inks, and pigments; including 11 dyes that are produced commercially in the United States. Human exposure to p-Cresidine occurs primarily through inhalation of

Carcinogenicity

p-Cresidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

2-Methoxy-5-methylaniline(120-71-8)Related Product Information

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