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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Biochemical Reagents >  3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one

3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one

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3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one Basic information

Product Name:
3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
Synonyms:
  • 3',6'-dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3h),9'-[9h]xanthen]-3-one
  • 3',6'-Dihydroxy-6-isothiocyanato-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
  • FLUORESCEIN-6-ISOTHIOCYANATE
  • Fluorescein-4-isothiocyanate (FITC-II)
  • Fluorescein 6-isothiocyanate isoMer I
  • 6-FITC, >97%
  • Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-4-isothiocyanato-
  • 3',6'-Dihydroxy-4-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
CAS:
3326-31-6
MF:
C21H11NO5S
MW:
389.38
Product Categories:
  • FLUOROPHORES
Mol File:
3326-31-6.mol
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3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one Chemical Properties

Boiling point:
722.7±60.0 °C(Predicted)
Density 
1.54±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
9.31±0.20(Predicted)
form 
Solid
color 
Light brown to brown
Appearance
Solid
InChI
InChI=1S/C21H11NO5S/c23-11-4-6-13-17(8-11)26-18-9-12(24)5-7-14(18)21(13)15-2-1-3-16(22-10-28)19(15)20(25)27-21/h1-9,23-24H
InChIKey
NUKUMXUIWPGENW-UHFFFAOYSA-N
SMILES
C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C(N=C=S)=CC=C1)C(=O)O2
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-42/43
Safety Statements 
26-36
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3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one Usage And Synthesis

Description

Fluorescein-6-isothiocyanate is a fluorescent dye widely used in biomedicine for various applications. It is commonly employed for labeling proteins, antibodies, and other biomolecules for visualization and tracking purposes in biological research. Additionally, this product is utilized in immunofluorescence assays and flow cytometry to detect and analyze specific markers and antigens. Its unique properties make it a valuable tool in the study of drug delivery, cell imaging, and disease diagnosis.

Uses

6-Fluorescein Isothiocyanate is a fluorescent reagent used in fluorescence polarization binding assay to develop inhibitors of inactive p38α Mitogen-activated protein kinase (MAPK).

Excitation / Emission Maximum

490-500 nm/510-525 nm

3',6'-Dihydroxy-6-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-oneSupplier

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