Basic information Safety Supplier Related

ACETATE KINASE

Basic information Safety Supplier Related

ACETATE KINASE Basic information

Product Name:
ACETATE KINASE
Synonyms:
  • EC 2.7.2.1
  • EC: 2.7.2.1
  • ATP: ACETATE PHOSPHOTRANSFERASE
  • Kinase (phosphorylating), acetate
  • ACETATE KINASE FROM ESCHERICHIA COLI
  • ACETATE KINASE FROM BACILLUSSTEAROTHERMO PHILUS
  • ACETATE KINASE FROM E. COLI, ~150 U/MG P ROTEIN
  • ACETATE KINASE FROM METHANOSARCINATHERMO PHILA RECO
CAS:
9027-42-3
MW:
0
EINECS:
232-818-0
Product Categories:
  • enzyme
Mol File:
Mol File
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ACETATE KINASE Chemical Properties

storage temp. 
2-8°C
form 
lyophilized powder
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
24/25
RIDADR 
UN 1789 8 / PGIII
WGK Germany 
3
10

MSDS

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ACETATE KINASE Usage And Synthesis

Uses

Acetate kinase is used to phosphorylate acetate to acetyl phosphate. Acetate Kinase from Bacillus stearothermophilus has been used to study allosteric activation. [32P]-acetyl phosphate was generated by incubating potassium acetate in the reaction mixture with acetate kinase from Sigma. This [32P]-acetyl phosphate was used to label BldM, BldM D-54N or BldM D-54A loci during the study of the effect of bldM gene on Streptomyces coelicolor development.

Uses

Acetate kinase is used to phosphorylate acetate to acetyl phosphate. Acetate Kinase from Escherichia coli has been used as part of an ATP-regenerating system to study the kinetics of agonist-stimulated transphosphatidylation .

General Description

Acetate kinase belongs to acetate and sugar kinase/Hsc70/actin (ASKHA) structural superfamily. It exists as a dimer and has nucleotide binding site in the cleft between N and C-terminal domain.

Biochem/physiol Actions

Acetate kinase plays an important role in glycolysis. Acetate kinase phosphorylates acetate in the presence of ATP and a divalent cation, which ultimately results in the production of acetyl-CoA. Acetate kinase is also involved in the metabolism of propanoate, pyruvate and taurine. Acetate Kinase from Bacillus stearothermophilus is a thermostable tetramer of identical subunits with molecular weight of 40,000 Da each. The enzyme does not have a -SH group and is composed of 36% β-structure, 21 % α-helix and 43 % unordered structure.

ACETATE KINASESupplier

Sinopharm Chemical Reagent Co,Ltd.
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86-21-63210123
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sj_scrc@sinopharm.com
Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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waley188@sohu.com
Nanjing Sunlida Biological Technology Co., Ltd.
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025-57798810
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sales@sunlidabio.com
Sigma-Aldrich
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021-61415566 800-8193336
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orderCN@merckgroup.com
Guangzhou Tomums Life Science Co., Ltd.
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020-31155029 18902330969
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sales@tomums.cn