diglycyl-histidine Chemical Properties

Melting point:

>210 °C (decomp)

Boiling point:

813.8±65.0 °C(Predicted)

Density 

1.440

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

pka

2.82±0.10(Predicted)

form 

solid

color 

white

Safety Information

WGK Germany 

3

diglycyl-histidine Usage And Synthesis

Uses

Gly-Gly-His has been used:

• as a peptide test probe in the hydrophilic interaction liquid chromatography (HILIC) studies
• in the electrochemical modification of back-side contact transducers (BSC) electrodes in copper (Cu2+) sensing studies
• for the fabrication carbon nanotube electrode for detection of Cu2+ ions

Definition

ChEBI: Gly-Gly-His is an oligopeptide.

Biological Activity

Gly-Gly-His (GGH) tripeptide displays the affinity of copper (Cu2+) complexation. These complexes display good skin tolerance and may be useful in wound healing. GGH copper complexes are proposed to reduce tumor necrosis factor α (TNF-α)-based interleukin 6 (IL-6) secretion by in vivo studies with fibroblasts. GGH is used in comparative studies with other imidazole-containing peptides such as carnosine. An area of active application research involves the GGH binding of copper ions.

diglycyl-histidine(7451-76-5)Related Product Information

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• N-Glycyl-L-tyrosine
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• Glycinamide hydrochloride
• Glycine tert butyl ester hydrochloride
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• GLY-ARG 4-METHOXY-BETA-NAPHTHYLAMIDE DIHYDROCHLORIDE
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• GLYCYL-L-ASPARTIC ACID