4-methyl-6-phenyl-2H-pyranone Chemical Properties

InChI

InChI=1S/C12H10O2/c1-9-7-11(14-12(13)8-9)10-5-3-2-4-6-10/h2-8H,1H3

InChIKey

AFUWPRQLOLYFDT-UHFFFAOYSA-N

SMILES

C1(=O)OC(C2=CC=CC=C2)=CC(C)=C1

4-methyl-6-phenyl-2H-pyranone Usage And Synthesis

Uses

4-Methyl-6-phenyl-2H-pyranone can be used for the synthesis of N-hydroxypyridone derivatives, which can protect astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality[1].

References

[1] Singh S, et al. Discovery of a novel series of N-hydroxypyridone derivatives protecting astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality. Bioorg Med Chem. 2017;25(4):1394-1405. DOI:10.1016/j.bmc.2016.12.052

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