ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Other amino acid derivatives > (R)-1-Boc-3-Aminopiperidine
(R)-1-Boc-3-Aminopiperidine
(R)-1-Boc-3-Aminopiperidine Basic information
- Product Name:
- (R)-1-Boc-3-Aminopiperidine
- Synonyms:
-
- tert-Butyl (3R)-3-aminopiperidine-1-carboxylate
- (R)-3-Aminopiperidine, N1-BOC protected
- (R)-1-t-Butyloxycarbonyl-3-aminopiperidine hydrochloride
- (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate
- (R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine
- 1-TERT-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE
- 1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester,(3R)-(9CI)
- (R)-3-AMINO-N-BOC-PIPERIDINE
- CAS:
- 188111-79-7
- MF:
- C10H20N2O2
- MW:
- 200.28
- EINECS:
- 628-472-9
- Product Categories:
-
- CHIRAL CHEMICALS
- Piperidines
- AMINOACID
- pharmacetical
- Piperidine
- Piperidine Series
- Mol File:
- 188111-79-7.mol
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(R)-1-Boc-3-Aminopiperidine Chemical Properties
- alpha
- 28.5 º (c=1, DMF)
- Boiling point:
- 277.3±33.0 °C(Predicted)
- Density
- 1.041±0.06 g/cm3(Predicted)
- refractive index
- 1.4730
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
- pka
- 10.35±0.20(Predicted)
- form
- Liquid
- color
- Colorless to pale yellow
- optical activity
- [α]/D -28.5±2°, c = 1 in DMF
- Water Solubility
- Immiscible with water.
- Sensitive
- Moisture Sensitive
- InChI
- InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
- InChIKey
- AKQXKEBCONUWCL-MRVPVSSYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
- CAS DataBase Reference
- 188111-79-7(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- RIDADR
- UN2735
- WGK Germany
- 3
- F
- 10-34
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29333990
MSDS
- Language:English Provider:SigmaAldrich
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(R)-1-Boc-3-Aminopiperidine Usage And Synthesis
Chemical Properties
Yellow liquid
Uses
(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.
Uses
(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.
General Description
(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.
(R)-1-Boc-3-AminopiperidineSupplier
Chengdu Firster Pharmaceutical Co., Ltd. Gold
- Tel
- 028-87078428 028-87074958
- chengzhenyong@cdfirster.com
Chengdu Aminotp Pharmaceutical Technology Co.,Ltd. Gold
- Tel
- 028-85755578 18140172005
- sales@aminotp.com
Shanghai NAIFU Biotechnology Co., Ltd Gold
- Tel
- 18939876937 18939876937
- sales@naifuchem.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
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(R)-1-Boc-3-Aminopiperidine(188111-79-7)Related Product Information
- Glycine
- Haloperidol
- 3-AMINOPIPERIDINE
- tert-Butyl carbazate
- N-Carbobenzyloxyglycine
- tert-Butanol
- 6-Aminocaproic acid
- ALTRENOGEST
- Tris(hydroxymethyl)aminomethane
- 8-Bromo-3-methyl-xanthine
- 2-Aminoacetophenone
- (R)-Boc-Nipecotic acid
- Diphenoxylate
- 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)-
- 1,1'-Diacetylferrocene
- (R)-1-Boc-3-Aminopiperidine-3-carboxylic acid
- (R)-1-N-BOC-3-METHYLAMINO PIPERIDINE
- Piperidine