PAPA NONOATE Chemical Properties

Boiling point:

277.2±42.0 °C(Predicted)

Density 

1.20±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Soluble in Water or Ethanol.

form 

White to off-white solid.

pka

5.55±0.69(Predicted)

color 

Off-white

Stability:

Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use.

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

PAPA NONOATE Usage And Synthesis

Description

PAPA NONOate (146672-58-4) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of PAPA NONOate in 0.1 M phosphate buffer at pH 7.4 is 15 minutes at 37°C, or 77 minutes at room temperature.1?Dissociation is essentially instantaneous at a pH of 5.0.

Uses

PAPA NONOate is an NO donor which suppresses the caspase apoptotic cascade.

Definition

ChEBI: PAPA NONOate is an alkylamine.

References

1) Keefer?et al. (1996),?‘NONOates’ (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol.,?268?281

PAPA NONOATE(146672-58-4)Related Product Information

• Sodium nitroprusside dihydrate
• NOC-18
• NOC-7
• MAHMA NONOATE
• 4-(N-CYANOMETHYL-N-NITROSO)AMINOMORPHOLINE
• S-NITROSOGLUTATHIONE
• NOC-5
• DEA NONOate
• GEA 5024
• Vorinostat
• NOC-12
• V-PYRRO/NO
• GEA 3162
• BETA-GAL-NONOATE
• NOR-3
• DPTA NONOATE
• SPERMINE NONOATE
• PAPA NONOATE