1,11-DIAZIDO-3,6,9-TRIOXAUNDECANE Chemical Properties

Density 

1.170 g/mL at 25 °C

refractive index 

n20/D1.470

storage temp. 

-20°C

solubility 

Soluble in chloroform, DCM, DMF, DMSO, or THF

form 

Oil

color 

Clear Colourless

Appearance

colorless liquid

Boiling point:

163-196°C/760 mmHg

InChI

InChI=1S/C8H16N6O3/c9-13-11-1-3-15-5-7-17-8-6-16-4-2-12-14-10/h1-8H2

InChIKey

SFMMXKLNFMIUCH-UHFFFAOYSA-N

SMILES

O(CCOCCN=[N+]=[N-])CCOCCN=[N+]=[N-]

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29270000

1,11-DIAZIDO-3,6,9-TRIOXAUNDECANE Usage And Synthesis

Description

PEG4 diazide is a hydrophilic linker with two azide groups. Both can be modified by click chemistry, either by a copper catalyzed reaction with terminal alkynes, or by a copper-free reaction with cycloalkynes. Azides can also participate in the Staudinger ligation reaction.

This diazide is useful for the synthesis of dimeric molecules by click chemistry.

Chemical Properties

Yellowish Oil

Uses

Homobifunctional PEG azide click chemistry linker. Azide functional groups will react via a copper catalyzed or strain promoted 1,3-dipolar cycloaddition click reaction with terminal alkynes and cyclooctyne derivatives to yield a stable triazole linkage.

Uses

1,11-Diazido-3,6,9-trioxaundecane is a useful linker for biomolecules.

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

IC 50

PEGs

1,11-DIAZIDO-3,6,9-TRIOXAUNDECANE(101187-39-7)Related Product Information

• Azido-PEG3-Sulfone-PEG4-acid
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• Azido-PEG3-NHS ester
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• 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
• N3-PEG3-Hydrazide
• Azido-PEG3-Sulfone-PEG4-t-butyl ester
• Azido-dPEG4-acid
• N3-PEG3-tBu
• 1-AZIDO-3,6,9-TRIOXAUNDECANE-11-OL
• Azido-PEG2-acid
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• H2N-PEG2-tBu
• 15-Azido-4,7,10,13-tetraoxapentadecanoic acid
• N3-PEG4-tBu
• 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE