11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE Chemical Properties

Boiling point:

198-202°C

Density 

1.10 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.470

storage temp. 

Amber Vial, Refrigerator, Under Inert Atmosphere

solubility 

miscible with water, polar organic solvents

form 

Viscous Liquid

color 

Yellow to Pale Brown

Appearance

colorless to yellowish liquid

BRN 

4745506

Stability:

Light Sensitive

InChI

InChI=1S/C8H18N4O3/c9-1-3-13-5-7-15-8-6-14-4-2-11-12-10/h1-9H2

InChIKey

FPVCVHVTMPCZTH-UHFFFAOYSA-N

SMILES

C(OCCOCCN)COCCN=[N+]=[N-]

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2735 8/PG 3

WGK Germany 

3

F 

10-34

HazardClass 

8

PackingGroup 

III

HS Code 

29299090

11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE Usage And Synthesis

Description

Amino-PEG3-azide is a bifunctional PEG linker containing an amino group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Chemical Properties

Very Pale Yellow Oil

Uses

A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.

Uses

11-Azido-3,6,9-trioxaundecan-1-amine is an azide with polyethylene glycol-like characteristics that can be used to prepare azide-functionalized polymers via click reaction.

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE(134179-38-7)Related Product Information

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