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11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE

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11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE Basic information

Product Name:
11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE
Synonyms:
  • Azido-PEG3-NH2
  • 11-Azido-3,6,9-trioxaundecylamine 97%
  • H2N-PEG(3)-N3
  • 1-Amino-11-azido-3,6,9-trioxaundecane, 2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethylamine, O-(2-Aminoethyl)-Oμ-(2-azidoethyl)diethylene glycol
  • 1-Amino-11-azido-3,6,9-trioxaundecane
  • 11-Azido-3,6,9-trioxaundecane-1-amine
  • N3-PEG3-CH2CH2NH2
  • 11-Azido-3,6,9-trioxaundecylamine
CAS:
134179-38-7
MF:
C8H18N4O3
MW:
218.26
Product Categories:
  • Aliphatics
  • Amines
  • Nitric Oxide Reagents
  • Cross Linking Reagents
  • Polyethyleneglycol Derivatives
  • Phosphorylating and Phosphitylating Agents
  • peg
Mol File:
134179-38-7.mol
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11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE Chemical Properties

Boiling point:
198-202°C
Density 
1.10 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.470
storage temp. 
Amber Vial, Refrigerator, Under Inert Atmosphere
solubility 
miscible with water, polar organic solvents
form 
Viscous Liquid
color 
Yellow to Pale Brown
BRN 
4745506
Stability:
Light Sensitive
InChIKey
FPVCVHVTMPCZTH-UHFFFAOYSA-N
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2735 8/PG 3
WGK Germany 
3
10-34
HazardClass 
8
PackingGroup 
III
HS Code 
29299090
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11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE Usage And Synthesis

Description

Amino-PEG3-azide is a bifunctional PEG linker containing an amino group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Chemical Properties

Very Pale Yellow Oil

Uses

A PEG derivative, which contains a free amine that can be conjugated to biological molecules directly by an amide linkage (or via the corresponding isothiocyanate) and an azide that can be reduced to an amine for conjugation to other molecules. PEG derivatives are water soluble. Bifunctional water soluble compounds with flexible dimensions allow for conjugation of small molecules to proteins or molecular probes. 1-amino-11-azido-3,6,9-trioxaundecane can be reacted with small organic molecules for the synthesis of heterobifunctional compounds. It has been used to synthesize a mannose-fluorescein conjugate for the study of cell-surface mannose-specific lectins.

Uses

11-Azido-3,6,9-trioxaundecan-1-amine is an azide with polyethylene glycol-like characteristics that can be used to prepare azide-functionalized polymers via click reaction.

11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINESupplier

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