Fmoc-9-Amino-4,7-Dioxanonanoic acid Chemical Properties

Melting point:

95.0 to 99.0 °C

Boiling point:

621.0±50.0 °C(Predicted)

Density 

1.243±0.06 g/cm3 (20 ºC 760 Torr)

storage temp. 

2-8°C

solubility 

soluble in Methanol

form 

powder to crystal

pka

4.28±0.10(Predicted)

color 

White to Almost white

Safety Information

HS Code 

2924297099

Fmoc-9-Amino-4,7-Dioxanonanoic acid Usage And Synthesis

Description

Fmoc-N-amido-PEG2-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White crystalline powder

Uses

Fmoc-AEEP-OH is used in preparation of glucose-responsive insulin conjugates.

Fmoc-9-Amino-4,7-Dioxanonanoic acid(872679-70-4)Related Product Information

• ALPHA,OMEGA-BIS(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 10'000
• H2N-PEG2-tBu
• TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA
• 3,6,9,12,15-Pentaoxahexadecane-1-thiol
• 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID
• m-PEG8-NHS ester
• Maleimide-PEG4-NHS Ester
• 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-ol
• 3,6,9,12,15,21,24,27,30-Decaoxadotriacontane-1,32-diaMine
• N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE
• Biotin-PEG4-N3
• N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
• N3-PEG4-tBu
• 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL
• BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
• OCTAETHYLENE GLYCOL MONOMETHYL ETHER
• 9-biotinlaMino-4,7-dioxanonanoic acid N-hydroxysucciniMidyl ester
• HO-PEG5-tBu