N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Chemical Properties

Melting point:

101-103°C

Boiling point:

705.8±60.0 °C(Predicted)

Density 

1.166±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

Methanol (Slightly)

pka

13.90±0.40(Predicted)

form 

Solid

color 

Pale Yellow to Pale Beige

CAS DataBase Reference

359860-27-8

Safety Information

HS Code 

2942000090

N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE Usage And Synthesis

Description

Biotin-PEG3-amine is reactive with NHS ester or carboxylic acid in the presence of EDC or HATU. PEG3 increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Uses

(+)-Biotinyl 3,6,9-Trioxaundecanediamine is a biotin derivative and is used as a reagent in the synthesis of a potent, covalent BTK inhibitor for B-cell lymphoma.

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