Basic information Safety Supplier Related

DBCO-S-S-PEG3-Biotin

Basic information Safety Supplier Related

DBCO-S-S-PEG3-Biotin Basic information

Product Name:
DBCO-S-S-PEG3-Biotin
Synonyms:
  • DBCO-S-S-PEG3-Biotin
  • CAS_1430408-09-5
  • Biotin-PEG3-SS-DBCO
  • Dibenzocyclooctyne-S-S-PEG3-Biotin
  • N-[24-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-13,21,24-trioxo-3,6,9-trioxa-16,17-dithia-12,20-diazatetracos-1-yl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
  • inhibit,PROTAC Linkers,DBCO-S-S-PEG-3-biotin,Inhibitor,DBCOSSPEG3biotin,DBCO S S PEG3 biotin
  • Dibenz[b,f]azocine-5(6H)-butanamide, 11,12-didehydro-N-[25-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-7,21-dioxo-11,14,17-trioxa-3,4-dithia-8,20-diazapentacos-1-yl]-γ-oxo-
CAS:
1430408-09-5
MF:
C42H56N6O8S3
MW:
869.12
Mol File:
1430408-09-5.mol
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DBCO-S-S-PEG3-Biotin Chemical Properties

Boiling point:
1194.2±65.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
solubility 
DMSO : 100 mg/mL (115.06 mM; Need ultrasonic)
pka
13.90±0.40(Predicted)
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DBCO-S-S-PEG3-Biotin Usage And Synthesis

Description

DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. PEG spacer arm provides better solubility to the labeled molecules in aqueous media. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP.

DBCO-S-S-PEG3-BiotinSupplier

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