Biotin-PEG3-SH
Biotin-PEG3-SH Basic information
- Product Name:
- Biotin-PEG3-SH
- Synonyms:
-
- Biotin-PEG3-SH
- 1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]ethyl]-2-oxo-, (3aS,4S,6aR)-
- CAS:
- 1244028-52-1
- MF:
- C18H33N3O5S2
- MW:
- 435.6
- Mol File:
- 1244028-52-1.mol
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Biotin-PEG3-SH Chemical Properties
- Boiling point:
- 716.4±60.0 °C(Predicted)
- Density
- 1.179±0.06 g/cm3(Predicted)
- pka
- 9?+-.0.10(Predicted)
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Biotin-PEG3-SH Usage And Synthesis
Biological Activity
Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Biotin-PEG3-SHSupplier
Borenpharm Co., Ltd
- Tel
- 027-65563561
- sales@borenpharm.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com
Wuhan Borenpharm Co., Ltd
- Tel
- 027-65563561 18717150066
- 3207347307@qq.com
Shaanxi borno biotechnology co., LTD
- Tel
- +86-13759708231
- asherw9@hotmail.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223
- psaitong@jm-bio.com