Basic information Safety Supplier Related

BIOTINAMIDOCAPROYL HYDRAZIDE

Basic information Safety Supplier Related

BIOTINAMIDOCAPROYL HYDRAZIDE Basic information

Product Name:
BIOTINAMIDOCAPROYL HYDRAZIDE
Synonyms:
  • Biotin-LC-Hz
  • EZ-Link Biotin-LC-hydrazide
  • N-(+)-Biotinyl-6-aminohexanoic hydrazide
  • BIOTINAMIDOCAPROYL HYDRAZIDE
  • BIOTINAMIDOCAPROYL HYDRAZINE
  • BIOTIN-EPSILON-AMINOCAPROYL HYDRAZIDE
  • BIOTIN LC HYDRAZIDE
  • BIOTIN LC HYDRAZINE
CAS:
109276-34-8
MF:
C16H29N5O3S
MW:
371.5
Product Categories:
  • Biotinylation Reagents
  • biotinyl
Mol File:
109276-34-8.mol
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BIOTINAMIDOCAPROYL HYDRAZIDE Chemical Properties

Melting point:
195-196°C
Boiling point:
777.0±55.0 °C(Predicted)
Density 
1.188±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 25 mg/mL
form 
powder
pka
13.26±0.35(Predicted)
color 
White to Almost white
InChIKey
IJJWOSAXNHWBPR-HUBLWGQQSA-N
CAS DataBase Reference
109276-34-8(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
-
10-21
HS Code 
29349990

MSDS

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BIOTINAMIDOCAPROYL HYDRAZIDE Usage And Synthesis

Description

This is a hydrazide-activated biotinylation reagent used to label glycoproteins, carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Hydrazine moiety reacts with an aldehyde to form semi-permanent hydrazone bonds. The extended spacer arm helps to minimize steric hindrance.

Chemical Properties

mp 195°C

Uses

Biotinylation reagent with aminocaproic spacer for aldehyde groups (e.g., periodate-oxidized sugars) and carboxylic acids. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone bond formation.

Purification Methods

Suspend the hydrazide in ice-water (100mg/mL), stand overnight at 4o, filter and dry the solid in a vacuum. Recrystallise it from isoPrOH. RF is 0.26 on SiO2 plate using CHCl3/MeOH (7:3) as eluent. [O'Shannessy et al. Anal Biochem 163 204 1987.]

BIOTINAMIDOCAPROYL HYDRAZIDESupplier

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