Iminostilbene Chemical Properties

Melting point:

197 °C

Boiling point:

221 °C(lit.)

Density 

1.290 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.523(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

dioxane: 50 mg/mL, clear

form 

powder

pka

1.71±0.20(Predicted)

color 

yellow to orange

Water Solubility 

Soluble in ethyl acetate (25 mg/ml), water (partly), dioxane, chloroform, and DMSO.

BRN 

1343358

LogP

4.06

CAS DataBase Reference

256-96-2(CAS DataBase Reference)

NIST Chemistry Reference

o,o'-Iminostilbene(256-96-2)

EPA Substance Registry System

5H-Dibenz[b,f]azepine (256-96-2)

Safety Information

Hazard Codes 

C,Xi,N,Xn

Risk Statements 

34-51/53-22-36/37/38

Safety Statements 

26-36/37/39-45-61-27-24/25

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

10-21

Hazard Note 

Irritant

HS Code 

29339900

MSDS

• Language:English Provider:5H-Dibenz[b,f]azepine
• Language:English Provider:SigmaAldrich

Iminostilbene Usage And Synthesis

Chemical Properties

Yellow to orange-yellow fine powder

Uses

Iminostilbene is mainly used as a pharmaceutical intermediate for the production of carbamazepine, Oxcarbazepine, and rhodium catalyst ligand. It is a metabolite of of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain.

Application

Iminostilbene has good antioxidant effects. N-acetyl iminostilbene was synthesized by incubating iminostilbene (2.0020 g, 10.360 mmol) with acetic anhydride.

Preparation

iminostilbene synthesis: 10,11-Dihydro-5-dibenz(b,f)azepine [Iminodibenzyl, 494-19-9] as raw material was acylated by triphosgene, after bromination by bromine and dehydrobromination, reacted with sodium hydroxide in isopropanol to give Iminostilbene.

Definition

ChEBI: Iminostilbene is a mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings. It has a role as a marine xenobiotic metabolite. It is a mancude organic heterotricyclic parent and a dibenzoazepine.

General Description

5H-Dibenz[b,f]azepine, a tricyclic amine with a seven-membered ring, is commonly known as iminostilbene. It is used as an intermediate or a starting material in the synthesis of many anticonvulsant drugs.It is also used as a starting material to prepare pharmacologically important dibenzoazepine-pyridazine derivatives and synthesize olefinic multidentate ligand, which is used to prepare Rh(I) complexes.

Biochem/physiol Actions

2-(Bromomethyl)naphthalene is a fluorescent alkyl bromide. It causes the esterification of free carboxyl groups formed at the surface of polyethylene terephthalate by enzyme hydrolysis. It acts as organic electrophile in the P4S10/acyloin reaction.

Iminostilbene(256-96-2)Related Product Information

• Iminodibenzyl
• EC 2.6.1.2
• Iminodiacetonitrile
• Acetaminophen
• Iminodiacetic acid
• Dibenz[b,f]azepine-5-carbonyl chloride
• 10-Methoxy-2,2'-iminostilbene,10-METHOXY IMINOSTILBENE
• Depramine
• Amezepine
• OPIPRAMOL DIHYDROCHLORIDE
• 5-Cyano-5H-dibenz[b,f]azepine
• Iminostilbene-N-carboxamide
• N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene
• 2,2'-IMINOSTILBENE
• 10-Methoxy Iminostilbene Carbonylchloride
• Cycloheptatriene
• Bromine
• 3-Hydroxy Carbamazepine