Diethyl (tosyloxy)methylphosphonate Chemical Properties

Boiling point:

137°C/0.02mmHg(lit.)

Density 

1.255

refractive index 

1.4980 to 1.5020

storage temp. 

Inert atmosphere,2-8°C

solubility 

Chloroform (Sparingly), Dichloromethane, Ethyl Acetate, Methanol (Sparingly)

form 

Oil

color 

Clear Colourless to Pale Yellow

InChI

InChI=1S/C12H19O6PS/c1-4-16-19(13,17-5-2)10-18-20(14,15)12-8-6-11(3)7-9-12/h6-9H,4-5,10H2,1-3H3

InChIKey

UOEFFQWLRUBDME-UHFFFAOYSA-N

SMILES

P(COS(C1=CC=C(C)C=C1)(=O)=O)(=O)(OCC)OCC

CAS DataBase Reference

31618-90-3(CAS DataBase Reference)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

36/37/39

HS Code 

29309090

Diethyl (tosyloxy)methylphosphonate Usage And Synthesis

Chemical Properties

Pale Yellow Oil

Uses

Diethyl (tosyloxy)methylphosphonate is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.

Uses

Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.

Diethyl (tosyloxy)methylphosphonate(31618-90-3)Related Product Information

• Diethyl phthalate
• p-Toluenesulfonamide
• Acetonitrile
• Methanol
• Diethyl succinosuccinate
• Tosyl chloride
• Methyldiethoxyphosphine
• Methylparaben
• Ethyl p-toluenesulfonate
• Tosyl cyanide
• Mefenpyr-diethyl
• Diethyl carbonate
• Diethyl malonate
• TOLBUTAMIDE
• Ethyl propionylacetate
• Methyl acrylate
• Chloromethyl isopropyl carbonate
• Tenofovir