Basic information Safety Supplier Related

Benzyl-PEG8-THP

Basic information Safety Supplier Related

Benzyl-PEG8-THP Basic information

Product Name:
Benzyl-PEG8-THP
Synonyms:
  • Benzyl-PEG8-THP
  • Benzyl-PEG9-THP
  • Benzyl-PEG7-THP
  • CAS_1611489-00-9
  • 2H-Pyran, tetrahydro-2-[(25-phenyl-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl)oxy]-
  • 2-((1-Phenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)oxy)tetrahydro-2H-pyran
CAS:
1611489-00-9
MF:
C28H48O10
MW:
544.67
Mol File:
1611489-00-9.mol
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Benzyl-PEG8-THP Chemical Properties

Boiling point:
602.0±55.0 °C(Predicted)
Density 
1.11±0.1 g/cm3(Predicted)
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Benzyl-PEG8-THP Usage And Synthesis

Biological Activity

Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Benzyl-PEG8-THPSupplier

Borenpharm Co., Ltd
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Zhengzhou Acme Chemical Co., Ltd.
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Amatek Scientific Co. Ltd.
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Xi'an Confluore Biological Technology Co., Ltd.
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Henan Alfachem Co.,Ltd.
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0371-0371-55051623 18137891487
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