ChemicalBook > CAS DataBase List > 5-Bromo-2-iodopyridine

5-Bromo-2-iodopyridine

Product Name
5-Bromo-2-iodopyridine
CAS No.
223463-13-6
Chemical Name
5-Bromo-2-iodopyridine
Synonyms
2-IODO-5-BROMOPYRIDINE;CAS:223463-13-6;5-Brom-2-iodpyridin;5-bromo-2-lodopyridine;5-BROMO-2-IDIOPYRIDINE;5-BROMO-2-IODOPYRIDINE;5-CroMo-2-iodopyridine;2-iodine-5-broMopyridine;PYRIDINE, 5-BROMO-2-IODO-;5-Bromo-2-Iodopyridine99%
CBNumber
CB0111175
Molecular Formula
C5H3BrIN
Formula Weight
283.89
MOL File
223463-13-6.mol
More
Less

5-Bromo-2-iodopyridine Property

Melting point:
113-117 °C (lit.)
Boiling point:
258.8±20.0 °C(Predicted)
Density 
2.347±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO, Methanol (Slightly)
pka
-0.51±0.10(Predicted)
form 
Crystalline Powder
color 
White to beige
Sensitive 
Light Sensitive
BRN 
2119
Stability:
Light Sensitive
InChI
InChI=1S/C5H3BrIN/c6-4-1-2-5(7)8-3-4/h1-3H
InChIKey
HSNBRDZXJMPDGH-UHFFFAOYSA-N
SMILES
C1(I)=NC=C(Br)C=C1
CAS DataBase Reference
223463-13-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
IRRITANT, LIGHT SENSITIVE
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
569607
Product name
5-Bromo-2-iodopyridine
Purity
97%
Packaging
5g
Price
$44.52
Updated
2025/07/31
Sigma-Aldrich
Product number
569607
Product name
5-Bromo-2-iodopyridine
Purity
97%
Packaging
25g
Price
$80.5
Updated
2025/07/31
TCI Chemical
Product number
B2877
Product name
5-Bromo-2-iodopyridine
Purity
>97.0%(GC)
Packaging
5g
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
B2877
Product name
5-Bromo-2-iodopyridine
Purity
>97.0%(GC)
Packaging
25g
Price
$186
Updated
2025/07/31
TRC
Product number
B687630
Product name
5-Bromo-2-iodopyridine
Packaging
10g
Price
$65
Updated
2021/12/16
More
Less

5-Bromo-2-iodopyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

5-Bromo-2-iodopyridine may be used in the synthesis of the following:

  • 5-bromopyridyl-2-magnesium chloride via reaction with isopropylmagnesium chloride solution
  • 5-bromo-2-pyridylzinc iodide via treatment with active zinc in tetrahydrofuran
  • 5-bromo-2-(trifluoromethyl)pyridine via halogen/trifluoromethyl displacement reaction
  • (5-bromopyridin-2-yl)zinc(II) chloride via multi-step synthesis
  • 5,5′-dibromo-2,2′-bipyridine via multi-step synthesis

Synthesis

624-28-2

223463-13-6

The general procedure for the synthesis of 5-bromo-2-iodopyridine from 2,5-dibromopyridine was as follows: an aqueous solution of 57% hydriodic acid (HI) was added to a reaction system containing 2,5-dibromopyridine (12.60 g, 53.2 mmol) and sodium iodide (NaI, 11.40 g, 76 mmol). The reaction mixture was heated to reflux for 24 h, subsequently cooled to room temperature and diluted with 100 mL of water. The pH of the mixture was adjusted to alkaline with sodium bicarbonate (NaHCO3), and then treated with the addition of sodium dithionite (Na2S2O4) until the solution became colorless. The reaction mixture was extracted with dichloromethane (DCM, 5 x 60 mL), the organic phases were combined and dried over anhydrous sodium sulfate (Na2SO4). The solvent was removed by concentration under reduced pressure and the obtained residue was collected by filtration, washed with ether (Et2O, 60 mL) and dried over air to give 5-bromo-2-iodopyridine (8.28 g, 55% yield) as a light gray powder.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 17, p. 4528 - 4532
[2] Chemical Communications, 2012, vol. 48, # 8, p. 1120 - 1122
[3] European Journal of Organic Chemistry, 2003, # 8, p. 1559 - 1568
[4] Journal of Organic Chemistry, 2001, vol. 66, # 2, p. 605 - 608
[5] Organic Letters, 2004, vol. 6, # 26, p. 4905 - 4907

5-Bromo-2-iodopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXALDEHYDE
More
Less

5-Bromo-2-iodopyridine Suppliers

Americas 1 Belgium 1 China 349 Europe 3 France 1 Germany 6 India 23 Japan 2 Jordan 1 Poland 1 Switzerland 2 Ukraine 1 United Kingdom 13 United States 49 Global 453
XPERTICK (SHANDONG) BIO-PHARMACEUTICAL CO., LTD
Tel
21-58999881 15623240527
Email
emily@xtick.cn
Country
China
ProdList
57
Advantage
58
Shanghai EachChem Co., Ltd.
Tel
021-64196659 13564486206
Fax
021-6419-6702
Email
info@eachchem.com
Country
China
ProdList
50
Advantage
55
Changzhou Standard Chemicals Ltd.
Tel
0519-85607885 13776800733
Fax
+86 519 8552788
Email
email@standardschem.com
Country
China
ProdList
114
Advantage
62
Nanjing Chao Yi Biotechnology Co., Ltd.
Tel
025-52614296 17761738099
Fax
025-52614296
Email
cychemical@126.com
Country
China
ProdList
53
Advantage
55
Jiangxi Estik Technology Development Co., Ltd
Tel
21-58999881 18702614013
Email
business@xpertick.cn
Country
China
ProdList
43
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-021-61259138 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Suzhou Chireach Biomedical Technology Co., Ltd.
Tel
0512-65856968
Fax
0512-65647218
Email
sales@chireach.com
Country
China
ProdList
59
Advantage
70
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44734
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9360
Advantage
66
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7895
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11036
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9878
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Santai Labs, Inc.
Tel
519-85601385
Fax
+86 519 8560 1389
Email
marketing@santailabs.com
Country
China
ProdList
891
Advantage
62
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4005
Advantage
55
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1542
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18512615154 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9342
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Shanghai Hong-chuang Pharma Tech Co., Ltd.
Tel
18151128828
Fax
-
Email
hc-sales@foxmail.com
Country
China
ProdList
2648
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
42446
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
ShangHai D&B Biological Science and Technology Co.Ltd
Tel
400-008-9730,021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3991
Advantage
60
Jinan XuanDe Chemical Co., Ltd.
Tel
0531-88803958 18866891188
Fax
0531-82777287
Email
18853169188@163.com
Country
China
ProdList
192
Advantage
58
More
Less

View Lastest Price from 5-Bromo-2-iodopyridine manufacturers

Sichuan Zhuoyu Yantang Technology Co., Ltd.
Product
5-Bromo-2-iodopyridine 223463-13-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2025-08-21
Hebei Fengjia New Material Co., Ltd
Product
5-Bromo-2-iodopyridine 223463-13-6
Price
US $5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100000
Release date
2024-08-08
Hebei Chuanghai Biotechnology Co., Ltd
Product
5-Bromo-2-iodopyridine 223463-13-6
Price
US $8.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-22

223463-13-6, 5-Bromo-2-iodopyridineRelated Search:

Chromium picolinate 2,2'-Bipyridine 2,6-Lutidine 1-Hexadecylpyridinium bromide 2-Bromo-5-nitropyridine 2-Chloro-3-hydroxypyridine 2-Iodopyridine 5-Bromo-2-fluorobenzoic acid 5-Bromo-2-chlorobenzoic acid 5-Bromo-2-iodo-3-methylpyridine Bromine 5-Bromo-2-iodo-4-picoline 5-BROMO-2-IODOPYRIDIN-3-OL 5-BROMO-2-IODO-3-METHOXYPYRIDINE 3-BROMO-2,6-DIIODO-5-METHOXYPYRIDINE 3,5-DIBROMO-2-IODOPYRIDINE 4-BROMO-1-IODOISOQUINOLINE 5-BROMO-2-IODOPYRIDIN-3-YL ACETATE

  • 5-BROMO-2-IODOPYRIDINE 97%
  • 5-bromo-2-iodopyridine 97% 5g
  • 5-Bromo-2-iodopyridine, 98+%
  • 5-BROMO-2-IDIOPYRIDINE
  • 5-bromo-2-lodopyridine
  • 2-iodine-5-broMopyridine
  • 5-CroMo-2-iodopyridine
  • PYRIDINE, 5-BROMO-2-IODO-
  • 5-BROMO-2-IODOPYRIDINE
  • 2-IODO-5-BROMOPYRIDINE
  • 5-Bromo-2-Iodopyridine99%
  • JR-6788, 5-Bromo-2-iodopyridine, 97%
  • 5-Bromo-2-iodopyridine &gt
  • 5-Bromo-2-iodopyridine ISO 9001：2015 REACH
  • 5-Brom-2-iodpyridin
  • 2-Iodo-5-bromopyridine,98%
  • CAS:223463-13-6
  • 223463-13-6
  • C5H3BrIN
  • C5H3NBrI
  • Building Blocks
  • Pyridines
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyridines derivates
  • Heterocycle
  • Bromopyridines
  • Halopyridines
  • Iodopyridines
  • Heterocycles
  • alkyl Iodine|alkyl Iodine
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • blocks
  • Bromides
  • Iodides
  • Pyridines
  • Pyridine
  • pyridine derivative
  • Pyridine Series
  • Halides