Trimeprazine

Product Name: Trimeprazine
CAS No.: 84-96-8
Chemical Name: Trimeprazine
Synonyms: Teralen;Teralene;Alimezine;Bayer 1219;ALIMENAZINE;alimemazine;TRIMEPRAZINE;Trimeperazine;dl-Trimeprazine;Methylpromazine
CBNumber: CB0146078
Molecular Formula: C18H22N2S
Formula Weight: 298.45
MOL File: 84-96-8.mol

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Trimeprazine Property

Melting point:: 68°C
Boiling point:: bp0.3 150-175°
Density: 1.1163 (rough estimate)
refractive index: 1.6000 (estimate)
pka: pKa 9.00 (Uncertain)
Water Solubility: 0.942 mg/L
CAS DataBase Reference: 84-96-8
NIST Chemistry Reference: Trimeprazine(84-96-8)

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Safety

Hazardous Substances Data: 84-96-8(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

H318Causes serious eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0009048
Product name: TRIMEPRAZINE
Purity: 95.00%
Packaging: 25G
Price: $2122.31
Updated: 2021/12/16

Chemtos

Product number: T-7860
Product name: Trimeprazine-d6(Alimemazine-d6)HCl
Packaging: 10mg
Price: $1800
Updated: 2021/12/16

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Trimeprazine Chemical Properties,Usage,Production

Originator

Temaril,SKF,US,1958

Uses

antipruritic

Uses

Trimeprazine is used for treating itching during dermatitis of both allergic and nonallergic origin.

Definition

ChEBI: Trimeprazine is a member of phenothiazines.

Manufacturing Process

95% sodamide (2.77 grams) is added to a solution of phenthiazine (9.6 grams) in xylene (140 cc) at a temperature of 130°C and the mixture is heated with reflux for 2 hours.
A 0.61 N solution (90 cc) of 1-chloro-2-methyl-3-dimethylaminopropane in xylene is then added over 50 minutes and heating with reflux is continued for 20 hours. After cooling, the mixture is treated with water (40 cc) and N methanesulfonic acid (70 cc). The aqueous layer is washed with ether, treated with aqueous sodium hydroxide (density = 1.33; 10 cc) and extracted with ether.
The extract is dried over potassium carbonate and evaporated and the residue is distilled in vacuo. 3-(10-phenthiazinyl)-2-methyl-1-dimethylaminopropane (12.6 grams) is collected, distilling between 150° and 175°C under a pressure of about 0.3 mm Hg. By dissolving this base in acetone and adding ethereal hydrogen chloride, a hydrochloride is obtained, MP 216° to 217°C.

brand name

Temaril (Allergan).

Therapeutic Function

Antipruritic

Trimeprazine Preparation Products And Raw materials

Raw materials

Preparation Products

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Trimeprazine Suppliers

China 38 France 1 Germany 1 India 6 Italy 1 United Kingdom 1 United States 9 Global 57

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View Lastest Price from Trimeprazine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Trimeprazine 84-96-8
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-05-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: Trimeprazine 84-96-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-10

84-96-8, TrimeprazineRelated Search:

Bis(2-ethylhexyl)amine Diethanolamine METHDILAZINE HYDROCHLORIDE (200 MG) METHDILAZINE (200 MG) Etymemazine (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT MEQUITAZINE pecazine Trifluomeprazine OXOMEMAZINE methiomeprazine cyamemazine perimetazine Levomepromazine hydrochloride Trimeprazine tartrate (-)-2-[METHYLAMINO]-1-PHENYLPROPANE 2-[2-[4-[2-methyl-3-(10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethoxy]ethanol Phenothiazine

n,n,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine

10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-

dl-Trimeprazine

Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]- (6CI, 8CI)

Teralene

ALIMENAZINE

Trimeprazine (base and/or unspecified salts)

alimemazine

10-[2-Methyl-3-(dimethylamino)propyl]phenothiazine

10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine

10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-

Alimezine

Bayer 1219

Methylpromazine

N,N,2-Trimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine

Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-

Teralen

Trimeperazine

Alimemazine-d6 MALEATE SALT

TRIMEPRAZINE

dimethyl-(2-methyl-3-phenothiazin-10-yl-propyl)amine

N,N,2-triMethyl-3-(10H-phenothiazin-10-yl)propan-1-aMine

10H-Phenothiazine-10-propanaMine,N,N,b-triMethyl-

Trimeprazine USP/EP/BP

84-96-8

84-86-8

C18H22N2S

TEMARIL