Methyl thioglycolate

Product Name: Methyl thioglycolate
CAS No.: 2365-48-2
Chemical Name: Methyl thioglycolate
Synonyms: Methyl 2-mercaptoacetate;MTG;METHYL MERCAPTOACETATE;THIOGLYCOLIC ACID METHYL ESTER;MERCAPTOACETIC ACID METHYL ESTER;METG;usafek-7119;USAF ek-7119;Articaine-003;Methy Diglycolate
CBNumber: CB0165491
Molecular Formula: C3H6O2S
Formula Weight: 106.14
MOL File: 2365-48-2.mol

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Methyl thioglycolate Property

Melting point:: -24 °C
Boiling point:: 42-43 °C/10 mmHg (lit.)
Density: 1.187 g/mL at 25 °C (lit.)
refractive index: n20/D 1.466(lit.)
Flash point:: 86 °F
storage temp.: Store below +30°C.
solubility: 40g/l
form: Liquid
pka: 8.04±0.10(Predicted)
color: Clear colorless
Water Solubility: 40 g/L (20 ºC)
Sensitive: Air Sensitive
BRN: 506259
InChIKey: MKIJJIMOAABWGF-UHFFFAOYSA-N
CAS DataBase Reference: 2365-48-2(CAS DataBase Reference)
NIST Chemistry Reference: Acetic acid, mercapto-, methyl ester(2365-48-2)
EPA Substance Registry System: Acetic acid, mercapto-, methyl ester (2365-48-2)

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Safety

Hazard Codes: Xn,T
Risk Statements: 10-20/22-36/37/38-25
Safety Statements: 26-36/37-45-36/37/39-28A
RIDADR: UN 1992 3/PG 3
WGK Germany: 1
RTECS: AI7350000
TSCA: Yes
HazardClass: 3
PackingGroup: III
HS Code: 29309070
Hazardous Substances Data: 2365-48-2(Hazardous Substances Data)
Toxicity: mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 108995
Product name: Methyl thioglycolate
Purity: 95%
Packaging: 5g
Price: $36.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 108995
Product name: Methyl thioglycolate
Purity: 95%
Packaging: 100g
Price: $43.2
Updated: 2024/03/01

TCI Chemical

Product number: T1287
Product name: Methyl Thioglycolate
Purity: >98.0%(GC)
Packaging: 25g
Price: $25
Updated: 2024/03/01

TCI Chemical

Product number: T1287
Product name: Methyl Thioglycolate
Purity: >98.0%(GC)
Packaging: 100g
Price: $49
Updated: 2024/03/01

Alfa Aesar

Product number: L03783
Product name: Methyl mercaptoacetate, 98%
Packaging: 100g
Price: $29.65
Updated: 2024/03/01

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Methyl thioglycolate Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

Methyl thioglycolate was used in the preparation of 3-carbomethoxy-4- oxotetrahydrothiopyran, 2- and 4-carbomethoxy-3-oxotetrahydrothiophene. It is used to prepare methyl thioglycolate and aminoethanethiol conjugated gold nanorods.

Uses

Methyl Thioglycolate is an derivative of Thioglycolic Acid (T350760), an organic compound containing both a thiol and a carboxylic acid functional groups. Thioglycolic Acid and its derivatives are oft en used in organic synthesis as a nucleophile in thioglycolysis reactions and is also used as a S transfer agent for sulfonyl chloride synthesis. Methyl Thioglycolate have been studied for the its inf luence on neocarzinostatin activation and expression of DNA damage.

Production Methods

Adding thioglycollic acid with purity of between 70.0 and 96.0 percent and methanol with purity of between 95.0 and 99.9 percent into a reaction device according to the molar ratio of 1:1.3-4.0; subsequently, adding an activating agent into the reaction device, stirring and heating for reaction; and after the reaction is finished, carrying out separatory distillation on reaction products to obtain the methyl thioglycolate. The activating agent is a p-toluenesulfonic acid methanol solution with a mass concentration of between 20 and 30 percent, and the use amount is 0.5 to 1.0 percent of the total mass of relative input materials.

Application

Methyl thioglycolate is a chemical compound that is used in the pharmaceutical industry as an intermediate. It has been used to synthesize anti-inflammatory drugs, such as aspirin and ibuprofen, and also for the treatment of autoimmune diseases. Methyl thioglycolate binds to amino acids on the surface of bacteria, which prevents them from functioning properly. This binding causes the cells to stop growing and die.

Definition

Methyl thioglycolate are widely used in free-radical photoinitiated polymerization reactions. In particular, the use of methyl thioglycolate (MTG), CH3OC(O)CH2SH, results in greater photopolymerization reaction rates, attributed to a weakening of the sulfur–hydrogen bond by hydrogen bonding of the thiol group. MTG constitutes the smaller exponent of the series of CH3OC(O)(CH2)nSH compounds, reported as intermediated in the organic sulfur cycle in marine environments, produced by marine phytoplankton.

General Description

Methyl thioglycolate reacts with nonprotein component of the antitumor antibiotic neocarzinostatin to form 1:1 adduct. It reacts with isothiocyanate to form Rhodanine.

Methyl thioglycolate Preparation Products And Raw materials

Raw materials

Thioglycolic acid

Preparation Products

Methyl 3-amino-4-methylthiophene-2-carboxylate METHYL 3-CHLORO-4-METHYLTHIOPHENE-2-CARBOXYLATE METHYL 3-AMINO-6-METHYLTHIOPHENO[2,3-B]PYRIDINE-2-CARBOXYLATE 5-CHLORO-4-METHOXYTHIOPHENE-3-CARBOXYLIC ACID 3-AMINO-6-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Methyl 3-amino-4-phenylthiophene-2-carboxylate 5-CHLORO-4-METHOXYTHIOPHENE-3-CARBONYL CHLORIDE Methyl 4-oxotetrahydrothiophene-3-carboxylate 5-BROMO-4-METHOXYTHIOPHENE-3-CARBOXYLIC ACID 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Rhodanine-3-acetic acid 3-AMINOTHIOPHENE-2-CARBOXAMIDE Dimethyl 4-aminothiophene-2,3-dicarboxylate hydrochloride Methyl 3-amino-2-thiophenecarboxylate 3-CHLORO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL 3-CHLOROTHIOPHENE-2-CARBOXYLATE Methyl 3-hydroxythiophene-2-carboxylate 1-Benzothiophen-5-amine METHYL 3-AMINO-5-(TERT-BUTYL)THIOPHENE-2-CARBOXYLATE Thifensulfuron methyl 5-BROMO-4-METHOXYTHIOPHENE-3-CARBONYL CHLORIDE 4-METHOXYTHIOPHENE-3-CARBOXAMIDE 4-METHOXYTHIOPHENE-3-CARBOXYLIC ACID 4-Chlorothieno[3,2-d]pyrimidine 3-AMINO-5-(TERT-BUTYL)THIOPHENE-2-CARBOXAMIDE METHYL 4-METHOXYTHIOPHENE-3-CARBOXYLATE 5-NITRO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID METHYL 7-AMINOTHIENO[2,3-B]PYRAZINE-6-CARBOXYLATE

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View Lastest Price from Methyl thioglycolate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Methyl thioglycolate 2365-48-2
Price: US $20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/Week
Release date: 2024-05-06

Hebei Weibang Biotechnology Co., Ltd

Product: Methyl thioglycolate 2365-48-2
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99.9%
Supply Ability: 20 tons
Release date: 2024-10-30

Hebei Weibang Biotechnology Co., Ltd

Product: Methyl thioglycolate 2365-48-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-30

2365-48-2, Methyl thioglycolateRelated Search:

POTASSIUM THIOGLYCOLATE Methyl 3-mercaptopropionate Methyl acrylate Methyl acetate Methyl glycolate 2-Ethylhexyl mercaptoacetate Kresoxim-methyl Ammonium thioglycolate ETHYL THIOGLYCOLATE Methylparaben METSULFURON METHYL Bensulfuron methyl Thiophanate-methyl Calcium thioglycolate Mercaptoacetic acid CYANOACETIC ACID-OSU calcium sulphidoacetate Methyl Methyl Mercaptoacetate

MERCAPTOACETIC ACID METHYL ESTER

METG

METHYL THIOGLYCOLATE

METHYL THIOGLYCOLLATE

METHYL MERCAPTOACETATE

THIOGLYCOLIC ACID METHYL ESTER

mercapto-aceticacimethylester

Methanethiol, methoxy-

methoxy-methanethio

Methyl 2-mercaptoacetate

Methyl alpha-mercaptoacetate

Methyl ester of thioglycolic acid

Methyl sulfanylacetate

methyl2-mercaptoacetate

Thioglykolsaeure-methylester

USAF ek-7119

usafek-7119

Sulfhydryl methyl acetate

Methylthioglycolate,98%

Acetic acid, mercapto-, methyl ester

Thioglyonic Acid Methyl Ester, ,

Methylmercaptoacetat

Thioglycol methylate

Thioglycollic acid methyl ester

Methyl thioglycolate,95%

Mercaptoacetic Acid Methyl Ester Methyl Mercaptoacetate Thioglycolic Acid Methyl Ester

Methy Diglycolate

Methyl thioglycolate,Methyl mercaptoacetate

Methyl thioglycolate, 95% 100GR

Methyl thioglycolate, 95% 500GR

Methyl thioglycolate, 95% 5GR

Methyl mercaptoacetate Methyl thioglycolate Mercaptoacetic acid methylester

Methyl mercaptoacetate Mercaptoacetic Acid Methyl Ester Thioglycolic Acid Methyl Ester

Methylethioglycolate

Methyl sulphanylacetate, Methyl mercaptoacetate

Acetic acid,2-Mercapto-, Methyl ester

Methyl thioglycolate 95%

Methyl thioglycolate, 99%, 99%

Methyl thioglycolate Joyce

MTG

Articaine-003

METHYL THIOGLYCOLATE Extra Pure

Tetramethylammonium hydroxide pentahydrate 10424-65-4

2365-48-2

HSCH2CO2CH3

HSCH2COOCH3

Organic Building Blocks

Thiols/Mercaptans

Sulfur Compounds

Building Blocks

2365-48-2