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L-KAWAIN

Product Name
L-KAWAIN
CAS No.
500-64-1
Chemical Name
L-KAWAIN
Synonyms
KAWAIN;gonosan;L-KAWAIN;Nsc112162;(R)-KAWAIN;(R)-(+)-Kavain;Kawain (200 mg);L-KAWAIN USP/EP/BP;5,6-Dihydro-4-methoxy-6-styryl-2-pyron;5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one
CBNumber
CB0182759
Molecular Formula
C14H14O3
Formula Weight
230.26
MOL File
500-64-1.mol
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L-KAWAIN Property

Melting point:
142-148℃
alpha 
D20 +105° (abs alc)
Boiling point:
bp0.1 195-197°
Density 
1.1914 (rough estimate)
refractive index 
1.5557 (estimate)
storage temp. 
Amber Vial, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
color 
White to Light Yellow
Stability:
Light Sensitive
LogP
0.784 (est)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2932202000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26524
Product name
Kavain
Packaging
50mg
Price
$78
Updated
2024/03/01
Cayman Chemical
Product number
26524
Product name
Kavain
Packaging
100mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
26524
Product name
Kavain
Packaging
10mg
Price
$32
Updated
2024/03/01
TRC
Product number
K145700
Product name
Kawain
Packaging
100mg
Price
$160
Updated
2021/12/16
TRC
Product number
K145700
Product name
Kawain
Packaging
200mg
Price
$265
Updated
2021/12/16
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L-KAWAIN Chemical Properties,Usage,Production

Originator

Largon,Klinge

Uses

Kawain is a plant extract that shows antioxidant activity through cyclooxygenase enzyme inhibition. May also be active in tumor suppression and apoptotic induction.

Definition

ChEBI: Kawain is a member of 2-pyranones and an aromatic ether.

Manufacturing Process

To 1170 g ethyl acetoacetate at 100-110°C was added a little at time 1605 g bromosuccinimide. After cooling to the mixture was added 300 ml of carbon tetrachloride. From the mixture was isolated ethyl ester of bromoacetoacetic acid which was distilled at 105-125°C/18 mm; yield 67%.
By condensation of the mixture 1400 g ethyl ester of bromoacetoacetic acid, 700 g bromosuccineimide, 500 ml benzene and 350 mg zinc was prepared (R)-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; melting point 157°C, yield 60-70%.

Therapeutic Function

Anesthetic; Tranquilizer

L-KAWAIN Preparation Products And Raw materials

Raw materials

Preparation Products

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L-KAWAIN Suppliers

China 87 India 1 United Kingdom 6 United States 14 USA 1 Global 109
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Whyte Chemicals
Tel
--
Fax
--
Email
sales@whytechemicals.co.uk
Country
United Kingdom
ProdList
3748
Advantage
50
Apin Chemicals Limited (UK)
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
Sequoia Research Products Ltd.
Tel
--
Fax
--
Email
sales@seqchem.com
Country
United Kingdom
ProdList
3113
Advantage
69
Apin Chemicals Ltd.
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
Advantage
42
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View Lastest Price from L-KAWAIN manufacturers

Wuhan Senwayer Century Chemical Co.,Ltd
Product
L-KAWAIN 500-64-1
Price
US $0.00-0.00/mg
Min. Order
5mg
Purity
99%
Supply Ability
40kg
Release date
2023-02-10
Shanghai Standard Technology Co., Ltd.
Product
Kawain 500-64-1
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-27
Career Henan Chemical Co
Product
L-KAWAIN 500-64-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-17

500-64-1, L-KAWAINRelated Search:

Tetracaine hydrochloride Aconitine VERATRIDINE TETRODOTOXIN QX-314 5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5<br>-dimethoxyphenylamide CLINODISIDE A N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride SDZ-201 106 (+/-) PD 85639 BATRACHOTOXIN DL-KAWAIN,KAWAIN 5,6-DIHYDRO-2H-PYRAN-2-ONE 4-phenyl-3-buten-2-ol 5,6-DIHYDRO-4-METHOXY-2H-PYRAN 5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE L-KAWAIN PARASORBICACID

  • 6-dihydro-4-methoxy-6-styryl-(r)-2h-pyran-2-on
  • gonosan
  • (R)-(+)-Kavain
  • [R-(E)]-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one
  • 5,6-Dihydro-4-methoxy-6-styryl-2-pyron
  • (6R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one
  • (R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one
  • 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]-
  • 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (+)-
  • 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (R)-
  • Nsc112162
  • 5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one
  • Kawain (200 mg)
  • KAWAIN
  • L-KAWAIN
  • (R)-KAWAIN
  • (r)-5,6-dihydro-4-methoxy-6-styryl-2h-pyran-2-one
  • 4-methoxy-6-(beta-phenylvinyl)-5,6-dihydro-alpha-pyrone
  • 5-hydroxy-3-methoxy-7-phenyl-2,6-heptadienoicacidgamma-lactone
  • 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)-
  • L-KAWAIN USP/EP/BP
  • (R,E)-4-Methoxy-6-styryl-5,6-dihydro-2H-pyran-2-one
  • TIANFU-CHEM_2H-Pyran-2-one,5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)- 500-64-1
  • γ-Aminobutyric acid Receptor,Calcium Channel,inhibit,Inhibitor,GABA Receptor,Gamma-aminobutyric acid Receptor,Na channels,Sodium Channel,Ca2+ channels,Ca channels,(+)-Kavain,(+) Kavain,Na+ channels,(+)Kavain
  • 500-64-1
  • 500-61-4
  • 315-48-4
  • Coumarins
  • Miscellaneous Natural Products