14,15-LEUKOTRIENE C4

Product Name: 14,15-LEUKOTRIENE C4
CAS No.: 75290-60-7
Chemical Name: 14,15-LEUKOTRIENE C4
Synonyms: EXC4;EOXIN C4;14,15-LTC4;14,15-LEUKOTRIENE C4;OBQVBASHEWLKCQ-PKBWNXTMSA-N;Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-13-carboxy-1-[(1S)-1-hydroxyhexyl]-2,4,6,9-tridecatetraen-1-yl]-L-cysteinyl-
CBNumber: CB0196624
Molecular Formula: C30H47N3O9S
Formula Weight: 625.77
MOL File: 75290-60-7.mol

More

Less

14,15-LEUKOTRIENE C4 Property

storage temp.: Store at -20°C
solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 100 μg/ml
form: Liquid.

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 10011360
Product name: 14,15-Leukotriene C4
Purity: ≥95%
Packaging: 25μg
Price: $127
Updated: 2024/03/01

Cayman Chemical

Product number: 10011360
Product name: 14,15-Leukotriene C4
Purity: ≥95%
Packaging: 50μg
Price: $236
Updated: 2024/03/01

Cayman Chemical

Product number: 10011360
Product name: 14,15-Leukotriene C4
Purity: ≥95%
Packaging: 100μg
Price: $447
Updated: 2024/03/01

TRC

Product number: L330368
Product name: 14,15-LeukotrieneC4
Packaging: 25μg
Price: $125
Updated: 2021/12/16

More

Less

14,15-LEUKOTRIENE C4 Chemical Properties,Usage,Production

Description

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTC₄ is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA₄ intermediates. 14,15-LTC₄ is classified as an eoxin, because it is formed mostly by eosinophils. However, mast cells and nasal polyps can synthesize 14,15-LTC₄ as well. Little is known about the physiological actions of 14,15-LTC₄. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs. However, in an in vitro permeability assay, 14,15-LTC₄ can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs resulting in plasma leakage - a hallmark of inflammation.

Uses

14,15-Leukotriene C4 is an acute inflammatory mediator.

14,15-LEUKOTRIENE C4 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

14,15-LEUKOTRIENE C4 Suppliers

China 23 Germany 1 United States 3 Global 27

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52925
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

BIOMOL INTERNATIONAL, LP

Tel: --
Fax: --
Email: info@biomol.com
Country: United States
ProdList: 1499
Advantage: 77

75290-60-7, 14,15-LEUKOTRIENE C4Related Search:

Ethyl isocyanoacetate PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Tosylmethyl isocyanide 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE SALCOMINE Cupric acetylacetonate TERT-BUTYL ISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE Benzyl isocyanide Aluminum acetylacetonate METHYL ISOCYANOACETATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Ferric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) N-BUTYLISOCYANIDE COBALT(II) ACETYLACETONATE

14,15-LEUKOTRIENE C4

14,15-LTC4

EOXIN C4

EXC4

OBQVBASHEWLKCQ-PKBWNXTMSA-N

Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-13-carboxy-1-[(1S)-1-hydroxyhexyl]-2,4,6,9-tridecatetraen-1-yl]-L-cysteinyl-

75290-60-7