2-Amino-6-chloro-3-nitropyridine

ChemicalBook > CAS DataBase List > 2-Amino-6-chloro-3-nitropyridine

2-Amino-6-chloro-3-nitropyridine

Product Name: 2-Amino-6-chloro-3-nitropyridine
CAS No.: 27048-04-0
Chemical Name: 2-Amino-6-chloro-3-nitropyridine
Synonyms: 6-CHLORO-3-NITROPYRIDIN-2-AMINE;LABOTEST-BB LT00012599;2-Amino-6-chloro-3-nitrop...;2-amino-3-nitrochloropyridine;6-Chlor-3-nitropyridin-2-amin;2-Amino-3-nitro-6-chloropyridi;2-Amino-6-chloro-nitro pyridne;2-Amino-6-chlor-3-nitropyridin;FlupirtinemaleateintermediateI;6-Chloro-3-nitro-2-pyridinamine
CBNumber: CB0245762
Molecular Formula: C5H4ClN3O2
Formula Weight: 173.56
MOL File: 27048-04-0.mol

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2-Amino-6-chloro-3-nitropyridine Property

Melting point:: 195-196
Boiling point:: 339.9±37.0 °C(Predicted)
Density: 1.596±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: Chloroform, DMSO
form: Crystalline
pka: -1.69±0.50(Predicted)
color: Yellow
Water Solubility: Slightly soluble in water. Soluble in dimethyl sulfoxide and chloroform.
InChI: InChI=1S/C5H4ClN3O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H,(H2,7,8)
InChIKey: WERABQRUGJIMKQ-UHFFFAOYSA-N
SMILES: C1(N)=NC(Cl)=CC=C1[N+]([O-])=O
CAS DataBase Reference: 27048-04-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-26-36/37/39
RIDADR: 2811
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A1756
Product name: 2-Amino-6-chloro-3-nitropyridine
Packaging: 5G
Price: $30
Updated: 2024/03/01

TCI Chemical

Product number: A1756
Product name: 2-Amino-6-chloro-3-nitropyridine
Packaging: 25G
Price: $89
Updated: 2024/03/01

Alfa Aesar

Product number: H64634
Product name: 2-Amino-6-chloro-3-nitropyridine, 98%
Packaging: 25g
Price: $68.65
Updated: 2024/03/01

Alfa Aesar

Product number: H64634
Product name: 2-Amino-6-chloro-3-nitropyridine, 98%
Packaging: 100g
Price: $222.65
Updated: 2024/03/01

TRC

Product number: A603495
Product name: 6-Amino-2-chloro-5-nitropyridine
Packaging: 25g
Price: $835
Updated: 2021/12/16

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2-Amino-6-chloro-3-nitropyridine Chemical Properties,Usage,Production

Description

2-Amino-6-chloro-3-nitropyridine is a cytotoxic drug that has been shown to have anti-viral potency, as well as antiviral activity in an activity test. It is synthesized by reacting hydrogen tartrate with oxadiazole, and then hydrolyzing the resulting product with chloride. 2-Amino-6-chloro-3-nitropyridine has also been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in vitro and to be effective against other viruses such as type 2 influenza. This drug can bind to the viral envelope and inhibit fusion of the viral membrane with host cells by preventing the release of viral contents into the cytoplasm. The binding affinity of 2-amino 6-chloro 3 nitropyridine for chloride may be due to hydrogen bonding interactions.

Chemical Properties

YELLOW POWDER

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Synthesis

The 2-Amino-6-chloro-3-nitropyridine may be obtained by the ammonolysis of 2,6-dichloro-3-nitropyridine by a known process. The ammonolysis is carried out by using solution of aqueous ammonia in methanol at 35°–40° C. After the reaction is over, the product is obtained by filtration.

2-Amino-6-chloro-3-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Flupirtine 6-Chloro-2,3-diaminopyridine 2,3-DIAMINO-6-CHLOROPYRIDINE N-(6-CHLORO-3-NITROPYRIDIN-2-YL)ACETAMIDE

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View Lastest Price from 2-Amino-6-chloro-3-nitropyridine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Amino-6-chloro-3-nitropyridine 27048-04-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-25

Zhengzhou Lingzhiyue Technology Co., Ltd

Product: 6-Chlor-3-nitropyridin-2-ylamin 27048-04-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 9999
Release date: 2023-10-28

Hebei Fengjia New Material Co., Ltd

Product: 2-Amino-6-chloro-3-nitropyridine 27048-04-0
Price: US $3.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000
Release date: 2024-09-03

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2-amino-3-nitro-6-chloropyridineQ: What is 2-amino-3-nitro-6-chloropyridine Q: What is the CAS Number of 2-amino-3-nitro-6-chloropyridine Q: What is the storage condition of 2-amino-3-nitro-6-chloropyridine Q: What are the applications of 2-amino-3-nitro-6-chloropyridine

6-Chloro-3-nitro pyridine-2-ylamine

6-Chlor-3-nitropyridin-2-ylamin

Product: 2-Amino-6-chloro-3-nitropyridine

27048-04-0

C5H4CIN2O2

Aromatics

Heterocycles

Miscellaneous Reagents

Pyridines

Pyridine

pyridine derivative

Amines

blocks

NitroCompounds