2-Amino-6-chloro-3-nitropyridine
- Product Name
- 2-Amino-6-chloro-3-nitropyridine
- CAS No.
- 27048-04-0
- Chemical Name
- 2-Amino-6-chloro-3-nitropyridine
- Synonyms
- 6-CHLORO-3-NITROPYRIDIN-2-AMINE;LABOTEST-BB LT00012599;2-Amino-6-chloro-3-nitrop...;2-amino-3-nitrochloropyridine;6-Chlor-3-nitropyridin-2-amin;2-Amino-3-nitro-6-chloropyridi;2-Amino-6-chloro-nitro pyridne;2-Amino-6-chlor-3-nitropyridin;FlupirtinemaleateintermediateI;6-Chloro-3-nitro-2-pyridinamine
- CBNumber
- CB0245762
- Molecular Formula
- C5H4ClN3O2
- Formula Weight
- 173.56
- MOL File
- 27048-04-0.mol
2-Amino-6-chloro-3-nitropyridine Property
- Melting point:
- 195-196
- Boiling point:
- 339.9±37.0 °C(Predicted)
- Density
- 1.596±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Chloroform, DMSO
- form
- Crystalline
- pka
- -1.69±0.50(Predicted)
- color
- Yellow
- Water Solubility
- Slightly soluble in water. Soluble in dimethyl sulfoxide and chloroform.
- InChI
- InChI=1S/C5H4ClN3O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H,(H2,7,8)
- InChIKey
- WERABQRUGJIMKQ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(Cl)=CC=C1[N+]([O-])=O
- CAS DataBase Reference
- 27048-04-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-26-36/37/39
- RIDADR
- 2811
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29333999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A1756
- Product name
- 2-Amino-6-chloro-3-nitropyridine
- Packaging
- 5G
- Price
- $30
- Updated
- 2024/03/01
- Product number
- A1756
- Product name
- 2-Amino-6-chloro-3-nitropyridine
- Packaging
- 25G
- Price
- $89
- Updated
- 2024/03/01
- Product number
- H64634
- Product name
- 2-Amino-6-chloro-3-nitropyridine, 98%
- Packaging
- 25g
- Price
- $68.65
- Updated
- 2024/03/01
- Product number
- H64634
- Product name
- 2-Amino-6-chloro-3-nitropyridine, 98%
- Packaging
- 100g
- Price
- $222.65
- Updated
- 2024/03/01
- Product number
- A603495
- Product name
- 6-Amino-2-chloro-5-nitropyridine
- Packaging
- 25g
- Price
- $835
- Updated
- 2021/12/16
2-Amino-6-chloro-3-nitropyridine Chemical Properties,Usage,Production
Description
2-Amino-6-chloro-3-nitropyridine is a cytotoxic drug that has been shown to have anti-viral potency, as well as antiviral activity in an activity test. It is synthesized by reacting hydrogen tartrate with oxadiazole, and then hydrolyzing the resulting product with chloride. 2-Amino-6-chloro-3-nitropyridine has also been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in vitro and to be effective against other viruses such as type 2 influenza. This drug can bind to the viral envelope and inhibit fusion of the viral membrane with host cells by preventing the release of viral contents into the cytoplasm. The binding affinity of 2-amino 6-chloro 3 nitropyridine for chloride may be due to hydrogen bonding interactions.
Chemical Properties
YELLOW POWDER
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Synthesis
The 2-Amino-6-chloro-3-nitropyridine may be obtained by the ammonolysis of 2,6-dichloro-3-nitropyridine by a known process. The ammonolysis is carried out by using solution of aqueous ammonia in methanol at 35°–40° C. After the reaction is over, the product is obtained by filtration.
2-Amino-6-chloro-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-6-chloro-3-nitropyridine Suppliers
- Tel
- --
- Fax
- --
- interchim@interchim.com
- Country
- France
- ProdList
- 6302
- Advantage
- 76
View Lastest Price from 2-Amino-6-chloro-3-nitropyridine manufacturers
- Product
- 2-Amino-6-chloro-3-nitropyridine 27048-04-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-25
- Product
- 6-Chlor-3-nitropyridin-2-ylamin 27048-04-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 9999
- Release date
- 2023-10-28
- Product
- 2-Amino-6-chloro-3-nitropyridine 27048-04-0
- Price
- US $3.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000
- Release date
- 2024-09-03